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Patogênese da Tuberculose: estudo com camundongos knockout para IFNy
(Sociedade Brasileira de Medicina Tropical, 2020)
Suppression of neuroinflammation in forebrain-specific Cdk5 conditional knockout mice by PPARγ agonist improves neuronal loss and early lethality
(BioMed Central Ltd., 2014)
Background: Cyclin-dependent kinase 5 (Cdk5) is essential for brain development and function, and its deregulated expression is implicated in some of neurodegenerative diseases. We reported earlier that the forebrain-specific ...
The contribution of TRPC1, TRPC3, TRPC5 and TRPC6 to touch and hearing
(Elsevier Ireland, 2016-01)
Transient receptor potential channels have diverse roles in mechanosensation. Evidence is accumulating that members of the canonical subfamily of TRP channels (TRPC) are involved in touch and hearing. Characteristic features ...
Knock-out
(Universidad, 2020)
In silico optimization of lipid production in Rhodosporidium toruloides by gene knockout strategies
(Elsevier Science, 2019-04)
Microbial lipids are being extensively studied as an alternative to vegetable oils in biodiesel production. For the biotechnological production of biolipids, efficient processes capable of obtaining significant biomass ...
Propriedade de membrana de neurônios do giro denteado em camundongos sem a enzima de reparo de DNA NEIL3
(BrasilUFRNPROGRAMA DE PÓS-GRADUAÇÃO EM PSICOBIOLOGIA, 2016-04-05)
This study aims to assess whether the expression of the DNA repair enzyme Neil3 is important for the functional development of neurons. Previous studies have demonstrated that Neil3 interferes with both adult and embryonic ...