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Metabolism regulates the spontaneous firing of substantia nigra pars reticulata neurons via KATP and nonselective cation channels
(Society for Neuroscience, 2014-12-03)
Neurons use glucose to fuel glycolysis and provide substrates for mitochondrial respiration, but neurons can also use alternative fuels that bypass glycolysis and feed directly into mitochondria. To determine whether ...
INGAP-PP up-regulates the expression of genes and proteins related to K-ATP(+) channels and ameliorates Ca2+ handling in cultured adult rat islets
(Elsevier B.V., 2008-06-05)
Islet Neogenesis Associated Protein (INGAP) increases pancreatic beta-cell mass and potentiates glucose-induced insulin secretion. Here, we investigated the effects of the pentadecapeptide INGAP-PP in adult cultured rat ...
INGAP-PP up-regulates the expression of genes and proteins related to K-ATP(+) channels and ameliorates Ca2+ handling in cultured adult rat islets
(Elsevier B.V., 2008-06-05)
Islet Neogenesis Associated Protein (INGAP) increases pancreatic beta-cell mass and potentiates glucose-induced insulin secretion. Here, we investigated the effects of the pentadecapeptide INGAP-PP in adult cultured rat ...
Muscarinic stimulation and pinacidil produce similar facilitation of tachyarrhythmia induction in rat isolated atria
(Academic Press Ltd- Elsevier Science LtdLondonInglaterra, 2013)
Precondicionamiento temprano contra las arrritmias de reperfusión en un modelo de oveja consciente. Rol de los canales de potasio dependientes de ATPEarly preconditioning against reperfusion arrhythmias in a conscious sheep model. Role of ATP-dependent potassium channels
(Federación Argentina de Cardiología, 2013-03)
Faltan evidencias claras de precondicionamiento temprano (PT) contra las arritmias de reperfusión en animales conscientes. Objetivo: Analizar la protección del PT contra las arritmias de reperfusión en un modelo ovino ...
Activation of the mitochondrial ATP-sensitive K+ channel reduces apoptosis of spleen mononuclear cells induced by hyperlipidemia
(BioMed CentralLondon, 2013)
Background
We have previously demonstrated that increased rates of superoxide generation by extra-mitochondrial enzymes induce the activation of the mitochondrial ATP-sensitive potassium channel (mitoKATP) in the livers ...
Participation of mitochondrial permeability transition pore in the effects of ischemic preconditioning in hypertrophied hearts: Role of NO and mitoKATP
(Elsevier Ireland, 2013-06)
Background: The mitochondrial permeability transition pore (mPTP) plays an important role in ischemia–reperfusion in normotensive animals. Our study aims to define their participation in the ischemic preconditioning (IP) ...
Hiperglicemia induz hiperalgesia mecânica e despolarização do potencial de repouso da membrana de neurônios nociceptivos primários: papel dos canais de potássio sensíveis ao ATPHyperglycemia induces mechanical hyperalgesia and depolarization of the resting membrane potential of primary nociceptive neurons: role of ATP-sensitive potassium channels
(Universidade Federal de UberlândiaBrasilPrograma de Pós-graduação em Ciências da Saúde, 2018)