Buscar
Mostrando ítems 1-10 de 17
Isradipine and lacidipine: Effects in vivo and in vitro on Trypanosoma cruzi epimastigotes
(PERGAMON-ELSEVIER SCIENCE LTD, 1998-01)
1. Isradipine and lacidipine, two new drugs that are members of the nitro-aryl-1,4-dihydropyridine family, produced inhibition of both growth cultures and oxygen consumption on epimastigotes of Trypanosoma cruzi Tulahuen ...
Hollow fiber-based liquid-phase microextraction (HF-LPME) of isradipine and its main metabolite followed by chiral HPLC analysis: application to an in vitro biotransformation study
(SPRINGER HEIDELBERG, 2011)
An enantioselective liquid chromatographic method using two-phase hollow fiber liquid-phase microextraction (HF-LPME-HPLC) was developed for the determination of isradipine (ISR) enantiomers and its main metabolite (pyridine ...
Decreased density of binding sites for the Ca2+ channel antagonist [3H] isradipine after denervation of rat vas deferens
(Elsevier B.V., 1994-05-02)
Radioligand binding assays were performed with the selective antagonist of dihydropyridine-sensitive Ca2+ channels [H-3]PN200-110 (isradipine) in rat vas deferens, before and 7 days after denervation, and data were compared ...
Efeitos da Isradipina (LOMIR). Agente inibidor de canais de cálcio, no processo de reparo em feridas de extração dental: estudo histológico em ratos
(Universidade Estadual Paulista (Unesp), 1995-06-08)
In order to make a histological evaluation of the dental alveolus wound healing in presence of the Isradipine (Lomir/Sandoz Pharma), the new calcium channels blockers, forthy-eight albino rats were utilized. These animals ...
Efeitos dos tratamentos com bloqueadores de canais de cálcio e resveratrol na locomoção de Drosophila melanogaster com modelo de parkinsonismo induzido por paraquat
(Pontifícia Universidade Católica do Rio Grande do SulPorto Alegre, 2010)
Studies have suggested that neuronal loss in Parkinson’s disease could be related to the pacemaker activity of the substantia nigra pars compacta generated by Ltype Cav1. 3 calcium channels, which progressively substitute ...
Efeitos dos tratamentos com bloqueadores de canais de cálcio e resveratrol na locomoção de Drosophila melanogaster com modelo de parkinsonismo induzido por paraquat
(Pontifícia Universidade Católica do Rio Grande do SulPorto Alegre, 2010)
Studies have suggested that neuronal loss in Parkinson’s disease could be related to the pacemaker activity of the substantia nigra pars compacta generated by Ltype Cav1. 3 calcium channels, which progressively substitute ...
Antioxidant effects of 1,4-dihydropyridine and nitroso aryl derivatives on the Fe+3/ascorbate-stimulated lipid peroxidation in rat brain slices
(PERGAMON-ELSEVIER SCIENCE, 1998-09)
1. Lipid peroxidation in rat brain slices was induced by Fe+3/ascorbate.
2. Brain lipid peroxidation, as measured by malondialdehyde formation, was inhibited by all the tested nitro aryl 1,4-dihydropyridine derivatives ...
Antioxidant effects of 1,4-dihydropyridine and niitroso aryl derivatives on the Fe+3/ascorbate-stimulated lipid peroxidation in rat brain slices
(1998)
Lipid peroxidation in rat brain slices was induced by Fe+3/ascorbate.Brain lipid peroxidation, as measured by malondialdehyde formation, was inhibited by all the tested nitro aryl 1,4-dihydropyridine derivatives over a ...
Relative reactivity of dihydropyridine derivatives to electrogenerated superoxide ion in DMSO solutions: A voltammetric approach
(KLUWER ACADEMIC/PLENUM PUBL, 2003-02)
Purpose. To evaluate the reaction of a large series of pharmacologically significant 1,4-dihydropyridine (1,4-DHP) compounds with superoxide (O-2(.-)) in dimethylsulfoxide using differential pulse voltammetry and controlled ...
Efeitos da Isradipina (LOMIR). Agente inibidor de canais de cálcio, no processo de reparo em feridas de extração dental: estudo histológico em ratos
(Universidade Estadual Paulista (UNESP), 2015)