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Induction of ischemic tolerance as a promising treatment against diabetic retinopathy
(Medknow Publications, 2014-09)
Diabetic retinopathy is a leading cause of acquired blindness, and it is the most common ischemic disorder of the retina. Available treatments are not very effective. Efforts to inhibit diabetic retinopathy have focused ...
Effects of Ischemic Preconditioning and Postconditioning in a Renal Ischemia-Reperfusion Injury Model: A Comparative Experimental Study in Rats
(Elsevier B.V., 2018-12-01)
Background. Ischemia-reperfusion injury is an unavoidable aspect of transplantation, as well as an important cause of acute kidney injury in clinical practice. Pre- and post-ischemic conditioning are strategies that may ...
Molecular mechanisms in liver ischemic-reperfusion injury and ischemic preconditioning
(SOCIEDAD MEDICA DE SANTIAGO, 2005)
Neuroprotective role of hypothermia in hypoxic-ischemic brain injury: Combined therapies using estrogen
(Bentham Science Publishers, 2018-12)
Hypoxic-ischemic brain injury is a complex network of factors, which is mainly characterized by a decrease in levels of oxygen concentration and blood flow, which lead to an inefficient supply of nutrients to the brain. ...
Molecular mechanisms in liver ischemic-reperfusion injury and ischemic preconditioning Mecanismos moleculares en el daño por isquemia-reperfusión hepática y en el preacondicionamiento isquémico
(2005)
Ischemia-reperfusion (IR) liver injury is associated with temporary clamping of hepatoduodenal ligament during liver surgery, hypoperfusion shock and graft failure after liver transplantation. Mechanisms of IR liver injury ...
High cholesterol diet effects on ischemia- reperfusion injury of the heart
(National Research Council Canada-NRC Research Press, 2012-09)
Ischemic heart disease is the leading cause of morbi-mortality in developed countries. Both ischemia-reperfusion injury and mechanisms of cardioprotection have been studied for more than 50 years. It is known that the ...
Neuroactivesteroids as neuroprotective agents against the neurodegenerative effects induced by perinatal hypoxia-ischemia injury
(Cambridge University Press, 2020-04)
Hypoxic-ischemic (HI) brain injury is one of main causes of long-term neurologic disability, morbidity and death worldwide in adults and children. This public health concern is mainly characterized by a decrease in oxygen ...
Implications of ischemic penumbra for the diagnosis of brain death
(Associação Brasileira de Divulgação Científica, 1999-12-01)
The data reviewed here suggest the possibility that a global reduction of blood supply to the whole brain or solely to the infratentorial structures down to the range of ischemic penumbra for several hours or a few days ...
The role of ischemic preconditioning and pentoxifylline in intestinal ischemia/reperfusion injury of rats
(Acta Cirurgica Brasileira, 2017)
Purpose: To investigate the role of ischemic preconditioning (IPC) and pentoxifylline (PTX) in intestinal mucosa ischemia/reperfusion injury (IR). Methods: Thirty rats were assigned to 5 groups (N= 6): (CG): no clamping ...
Ischemic preconditioning and tacrolimus pretreatment as strategies to attenuate intestinal ischemia-reperfusion injury in mice
(Elsevier, 2013-08)
The intestine is highly sensitive to ischemia-reperfusion injury (IRI), a phenomenon occurring in different intestinal diseases. Several strategies to mitigate IRI are in experimental stages; unfortunately, no consensus ...