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Iron and glutathione at the crossroad of redox metabolism in neurons
(Sociedad de Biología de Chile, 2006)
Cardiovascular outcomes of intravenous iron in perspective of clinical trials and the use of different iron preparations
(Elsevier Ireland, 2015-05)
In November 2014, an article by Kuo et al. suggested a role of an intravenous (i.v.) iron sucrose preparation in leukocyte?endothelium interactions and atherogenesis based on results in cell culture assays, a mouse model ...
Disturbance of redox homeostasis in Down Syndrome: Role of iron dysmetabolism
(Elsevier Inc., 2018)
Nitrosative stress and apoptosis in non-anemic healthy rats induced by intravenous iron sucrose similars versus iron sucrose originator
(Springer, 2015-04)
Iron can both induce and inhibit nitrosative stress. Intracellular iron levels play an important role in nitric oxide (NO•) signaling mechanisms. Depending on various factors, such as the cell's redox state and transition ...
Markers of oxidative/nitrosative stress and inflammation in lung tissue of rats exposed to different intravenous iron compounds
(Dove Press, 2017-08)
Iron deficiency anemia is a frequent complication in clinical conditions such as chronic kidney disease, chronic heart failure, inflammatory bowel disease, cancer, and excessive blood loss. Given the ability of iron to ...
Nitrosative Stress and Apoptosis by Intravenous Ferumoxytol, Iron Isomaltoside 1000, Iron Dextran, Iron Sucrose, and Ferric Carboxymaltose in a Nonclinical Model
(Thieme Medical Publ Inc, 2015-07)
Iron is involved in the formation as well as in the scavenging of reactive oxygen and nitrogen species. Thus, iron can induce as well as inhibit both oxidative and nitrosative stress. It also has a key role in reactive ...
Iron in neuronal function and dysfunction
(IOS Press, 2010-03)
Iron (Fe) is an essential element for many metabolic processes, serving as a cofactor for heme and nonheme proteins. Cellular iron deficiency arrests cell growth and leads to cell death; however, like most transition metals, ...
The Induction of Oxidative/Nitrosative Stress, Inflammation, and Apoptosis by a Ferric Carboxymaltose Copy Compared to Iron Sucrose in a Non-Clinical Model
(Premchand Shantidevi Research Foundation, 2015-12)
Introduction: Ferric carboxymaltose is a next-generation polynuclear iron(III)-hydroxide carbohydrate complex for intravenous iron therapy belonging to the class of so-called non-biological complex drugs. The product ...