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Intrinsic dissolution simulation of highly and poorly soluble drugs for BCS solubility classification
(Dissolution Technologies, Inc, 2017)
Intrinsic dissolution testing allows characterizing drug substances through its dissolution rate when exposed to a specified surface area in a specific dissolution media, This can be used to determine if a drug substance ...
Development and validation of an intrinsic dissolution method for nimodipine polymorphs
(Versita, 2014-05-01)
The polymorphs of nimodipine, Modification I (Mod I), the metastable racemate, and Modification II (Mod II), the stable conglomerate, were evaluated by means of the intrinsic dissolution procedure. for this purpose, a hydro ...
Solid dosage forms for active antiretroviral therapy (HAART): dissolution profile study of nevirapine by experimental factorial design
(Informa HealthcareLondonInglaterra, 2013)
Intrinsic Dissolution as a Tool for Evaluating Drug Solubility in Accordance with the Biopharmaceutics Classification System
(DISSOLUTION TECHNOLOGIES, INC, 2011)
The Biopharmaceutics Classification System (BCS) is a tool that was created to categorize drugs into different groups according to their solubility and permeability characteristics. Through a combination of these factors ...
Compatibility studies of nevirapine in physical mixtures with excipients for oral HAART
(Elsevier Science BvAmsterdamHolanda, 2013)
Influence of beta-cyclodextrin on the properties of norfloxacin form A
(Springer, 2015-06-01)
Cyclodextrins are able to form host-guest complexes with hydrophobic molecules to result in the formation of inclusion complexes. The complex formation between norfloxacin form A and beta-cyclodextrin was studied by exploring ...
Dissolution properties, solid-state transformation and polymorphic crystallization: Progesterone case study
(Taylor & Francis, 2014-11)
Progesterone is a natural steroid hormone and a poor soluble drug which presents two polymorphs (forms 1 and 2). Different methods to obtain form 2 were tested and a complete solid-state characterization of both polymorphs ...
Influence of β-cyclodextrin on the Properties of Norfloxacin Form A
(2014-12-16)
Cyclodextrins are able to form host-guest complexes with hydrophobic molecules to result in the formation of inclusion complexes. The complex formation between norfloxacin form A and β-cyclodextrin was studied by exploring ...