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Nitrosative Stress and Apoptosis by Intravenous Ferumoxytol, Iron Isomaltoside 1000, Iron Dextran, Iron Sucrose, and Ferric Carboxymaltose in a Nonclinical Model
(Thieme Medical Publ Inc, 2015-07)
Iron is involved in the formation as well as in the scavenging of reactive oxygen and nitrogen species. Thus, iron can induce as well as inhibit both oxidative and nitrosative stress. It also has a key role in reactive ...
Cardiovascular, liver, and renal toxicity associated with an intravenous ferric carboxymaltose similar versus the originator compound
(Dove Medical Press Ltd., 2017-11)
Background: Ferric carboxymaltose (FCM) is a stable, non-dextran-based intravenous iron complex used to treat iron deficiency of various etiologies. As FCM is a nonbiological complex drug and cannot be fully characterized ...
Optimizing iron delivery in the management of anemia: Patient considerations and the role of ferric carboxymaltose
(Dove Medical Press Ltd., 2014-12)
With the challenge of optimizing iron delivery, new intravenous (iv) iron-carbohydrate complexes have been developed in the last few years. A good example of these new compounds is ferric carboxymaltose (FCM), which has ...
Intravenous iron supplementation may protect against acute mountain sickness: A randomized, double-blinded, placebo-controlled trial
(Mary Ann Liebert, 2011)
Acute mountain sickness (AMS) is a common and disabling condition that occurs in healthy individuals ascending to high altitude. Based on the ability of iron to influence cellular oxygen sensing pathways, we hypothesized ...
Markers of oxidative/nitrosative stress and inflammation in lung tissue of rats exposed to different intravenous iron compounds
(Dove Press, 2017-08)
Iron deficiency anemia is a frequent complication in clinical conditions such as chronic kidney disease, chronic heart failure, inflammatory bowel disease, cancer, and excessive blood loss. Given the ability of iron to ...
Validación de la técnica para la medición de capacidad antioxidante total por fotoquimioluminiscencia
(2019-03-11)
RESUMEN:La fotoquimioluminiscencia (PCL) es una técnica que cuantifica el potencial
antioxidante a través de la luminiscencia emitida durante la excitación fotónica de
compuestos que contrarrestan la oxidación y con ello ...
Síntesis y funcionalización de (hetero)árenos mediante reacciones catalizadas por paladio o reducción de sulfóxidos: un enfoque hacia la obtención de 2-alquilbenzofuranos y otras moléculas de interés biológico
(Universidad de los AndesDoctorado en Ciencias - QuímicaFacultad de CienciasDepartamento de Química, 2022-07-22)
Este documento presenta los resultados experimentales más relevantes de la investigación realizada en el Laboratorio de Síntesis Orgánica, Bio y Organocatálisis del Departamento de Química de la Universidad de los Andes ...