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White adipose tissue IFN-γ expression and signalling along the progression of rodent cancer cachexia
(2017-01-01)
Cachexia is associated with increased morbidity and mortality in cancer. The White adipose tissue (WAT) synthesizes and releases several pro-inflammatory cytokines that play a role in cancer cachexia-related systemic ...
Therapeutic role of interferon-γ in experimental autoimmune encephalomyelitis is mediated through a tolerogenic subset of splenic CD11b+ myeloid cells
(2024)
Cumulative evidence has established that Interferon (IFN)-γ has both pathogenic and protective roles in Multiple Sclerosis and the animal model, Experimental Autoimmune Encephalomyelitis (EAE). However, the underlying ...
Phosphorylation of Mitogen-Activated Protein Kinases Contributes to Interferon γ Production in Response to Mycobacterium tuberculosis
(Oxford University Press, 2012-12)
Immune control of Mycobacterium tuberculosis depends on interferon γ (IFN-γ)–producing CD4+ lymphocytes. Previous studies have shown that T cells from patients with tuberculosis produce less IFN-γ, compared with healthy ...
(última autoría compartida) Cross-talk between CD31 and the signaling lymphocytic activation molecule-associated protein during interferon- gamma production against Mycobacterium tuberculosis.
(Oxford University Press, 2007-11)
Effective host defense against tuberculosis requires Th1 cytokine responses. We studied the regulation of interferon (IFN)-γ production during tuberculosis by investigating the role of CD31, a receptor that attenuates T ...
IFN-γ production during active tuberculosis is regulated by mechanisms that involve IL-17, SLAM, and CREB
(University of Chicago Press, 2009-03)
Interferon-γ (IFN-γ) is crucial for protection against Mycobacterium tuberculosis, and the transcription factor cAMP response element binding protein (CREB) increases IFN-γ transcription. We determined whether the transmembrane ...
Transforming growth factor-beta inhibits interferon-gamma-induced HLA-DR expression by cultured human fibroblasts
(1996)
This study shows the induction of HLA-DR (DR) in fibroblasts by IFN-γ and investigates the molecular mechanisms involved in the further DR down-regulation by TGF-β1. Kinetics of DR induction on human dermal fibroblasts by ...
Rol del factor de elongación-1α de la post-oncosfera de Taenia solium en la regulación de la vía de señalización del interferón-γ en la microglía
(Universidad Peruana Cayetano HerediaPE, 2024)
La neurocisticercosis es una infección del sistema nervioso central causada por el estadio larval de Taenia solium. La infección inicia con la ingesta de huevos del parásito que liberan una oncosfera en el intestino; la ...