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Behavioral characterization of a model of differential susceptibility to obesity induced by standard and personalized cafeteria diet feeding
(2015)
Despite the increase in obesity prevalence over the last decades, humans show large inter-individual variability for susceptibility to diet-induced obesity. Understanding the biological basis of this susceptibility could ...
Changes in gut microbiota due to supplemented fatty acids in diet-induced obese mice
(2013)
Consumption of a high-fat diet (HFD), which is associated with chronic ‘low-grade’ systemic inflammation, alters the gut microbiota (GM). The aim of the present study was to investigate the ability of an oleic acid-derived ...
Metformin attenuates the exacerbation of the allergic eosinophilic inflammation in high fat-diet-induced obesity in mice
(Public Library of ScienceSan Francisco, 2013-10-24)
A positive relationship between obesity and asthma has been well documented. The AMP-activated protein kinase (AMPK) activator metformin reverses obesity-associated insulin resistance (IR) and inhibits different types of ...
Metformin Attenuates the Exacerbation of the Allergic Eosinophilic Inflammation in High Fat-Diet-Induced Obesity in Mice
(Public Library Science, 2013-10-24)
A positive relationship between obesity and asthma has been well documented. the AMP-activated protein kinase (AMPK) activator metformin reverses obesity-associated insulin resistance (IR) and inhibits different types of ...
Hypothermic effect of acute citral treatment during lps-induced systemic inflammation in obese mice: reduction of serum tnf-α and leptin levels
(2020-10-01)
Citral is a mixture of monoterpenes present in the essential oil of several plants, such as Cymbopogon citratus and Zingiber officinale, possessing anti-inflammatory, anti-ulcerogenic, and antipyretic actions. We investigated ...
Obesity increases mitogen-activated protein kinase phosphatase-3 levels in the hypothalamus of mice
(2017-10-09)
Mitogen-activated Protein Kinase Phosphatase 3 (MKP-3) has been involved in the negative regulation of insulin signaling. The absence of MKP-3 is also associated with reduced adiposity, increased energy expenditure and ...
Bacteroides uniformis CECT 7771 ameliorates metabolic and immunological dysfunction in mice with high-fat-diet induced obesity
(Public Library of Science, 2012-07-26)
Background: Associations have been made between obesity and reduced intestinal numbers of members of the phylum Bacteroidetes, but there is no direct evidence of the role these bacteria play in obesity. Herein, the effects ...