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Streptozotocin-Induced Maternal Hyperglycemia Increases the Expression of Antioxidant Enzymes and Mast Cell Number in Offspring Rat Ventral Prostate
(Wiley-Blackwell, 2017-02-01)
Gestational diabetes mellitus (GDM) has increased in recent years. Although the cellular and molecular mechanisms involved in GDM-increased risk factors to offspring remained poorly understood, some studies suggested an ...
Streptozotocin-induced mechanical hypernociception is not dependent on hyperglycemia
(Associação Brasileira de Divulgação Científica, 2009)
Since streptozotocin (STZ)-induced diabetes is a widely used model of painful diabetic neuropathy, the aim of the present study was to design a rational protocol to investigate whether the development of mechanical ...
Cyclosporine A attenuates apoptosis and necrosis after ischemia-reperfusion-induced renal injury in transiently hyperglycemic rats
(2017-03-01)
Purpose: To investigate the effects of cyclosporine A on renal ischemia-reperfusion injury during transient hyperglycemia in rats. Methods: In a model of ischemia-reperfusion-induced renal injury and transiently induced ...
Neonatally induced diabetes: liver glycogen storage in pregnant rats
(Brazilian Archives of Biology and Technology, 2012-04-01)
The aim of this sstudy was to evaluate the liver glycogen storage in pregnant rats presenting neonatal streptozotocin-induced diabetes and to establish a relation with glycemia and insulin levels. Wistar rats were divided ...
Neonatally induced diabetes: liver glycogen storage in pregnant rats
(Brazilian Archives of Biology and Technology, 2012-04-01)
The aim of this sstudy was to evaluate the liver glycogen storage in pregnant rats presenting neonatal streptozotocin-induced diabetes and to establish a relation with glycemia and insulin levels. Wistar rats were divided ...
TRPC6 counteracts TRPC3-Nox2 protein complex leading to attenuation of hyperglycemia-induced heart failure in mice
(Sci Rep, 2017-08)
Excess production of reactive oxygen species (ROS) caused by hyperglycemia is a major risk factor for heart failure. We previously reported that transient receptor potential canonical 3 (TRPC3) channel mediates pressure ...
Neonatally induced diabetes: liver glycogen storage in pregnant rats
(Brazilian Archives of Biology and Technology, 2014)
Streptozotocin-induced leukocyte DNA damage in rats
(2018-01-01)
Although several studies using peripheral blood samples suggest that DNA damage is caused by streptozotocin (STZ) per se, our hypothesis is that DNA damage is caused by STZ-induced glycemic changes. Thus, we aimed at ...
Maternal-placental-fetal outcomes of neonatal streptozotocin-induced mild hyperglycemia in rats
(W B Saunders Co Ltd, 2008-01-01)