Background In vitro selection tests such as exposure to low pH and bile salts, competitive exclusion of pathogens, adherence to cell lines and prokaryotic-eukaryotic co-cultures have been commonly used to predict the ...

A strategy was developed to predict in-vivo plasma drug levels from data collected during in-vitro transdermal iontophoretic delivery experiments. The method used the principle of mass conservation and the Nernst-Planck ...