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Bovine derived in vitro cultures generate heterogeneous populations of antigen presenting cells
(Frontiers Media, 2019)
Antigen presenting cells (APC) of the mononuclear phagocytic system include dendritic cells (DCs) and macrophages (Macs) which are essential mediators of innate and adaptive immune responses. Many of the biological functions ...
Fungicidal activity of human monocyte-derived multinucleated giant cells induced in vitro by Paracoccidioides brasiliensis antigen
(Springer, 2008-07-01)
Multinucleated giant cells (MGC) are characteristic cells in granulomatous disorders such as paracoccidioidomycosis (PCM) and also are formed in vitro from peripheral blood mononuclear cells by several stimuli. In this ...
Fungicidal activity of human monocyte-derived multinucleated giant cells induced in vitro by Paracoccidioides brasiliensis antigen
(Springer, 2008-07-01)
Multinucleated giant cells (MGC) are characteristic cells in granulomatous disorders such as paracoccidioidomycosis (PCM) and also are formed in vitro from peripheral blood mononuclear cells by several stimuli. In this ...
Characterization and in vitro activities of cell-free antigens from Histoplasma capsulatum-loaded biodegradable microspheres
(ELSEVIER SCIENCE BV, 2009)
In the last decades, the incidence of histoplasmosis, a pulmonary fungal disease caused by Histoplasma capsulatum, has increased worldwide. In this context, vaccines for the prevention of this infection or therapies are ...
The capacity of Salmonella to survive inside dendritic cells and prevent antigen presentation to T cells is host specific
(WILEY-BLACKWELL, 2008)
Infection with Salmonella enterica serovar Typhimurium (S. Typhimurium) causes a severe and lethal systemic disease in mice, characterized by poor activation of the adaptive immune response against Salmonella-derived ...
Dead tumor cells expressing infectious salmon anemia virus fusogenic protein favor antigen cross-priming in vitro
(Frontiers media SA, 2017)
Antigen cross-presentation is a crucial step in the assembly of an antitumor immune response leading to activation of naive CD8 T cells. This process has been extensively used in clinical trials, in which dendritic cells ...
Eosinófilos como células apresentadoras de antígeno durante a infecção experimental por toxocara canis
(Universidade Federal de São CarlosUFSCarPrograma de Pós-Graduação em Genética Evolutiva e Biologia Molecular - PPGGEvCâmpus São Carlos, 2017-12-15)
Eosinophils are multifunctional cells that have pro-inflammatory cytotoxic activities and stimulate CD4 + T cells in experimental models of allergy and parasitic infections. Eosinophils, when exposed to antigens are activated ...
Neural and oligodendrocyte progenitor cells: transferrin effects on cell proliferation
(Portland Press, 2013-03)
NSC (neural stem cells)/NPC (neural progenitor cells) are multipotent and self-renew throughout adulthood in the SVZ (subventricular zone) of the mammalian CNS (central nervous system). These cells are considered interesting ...
Andrographolide interferes with t cell activation and reduces experimental autoimmune encephalomylitis in the mouse
(AMER SOC PHARMACOLOGY EXPERIMENTAL THERAPEUTICS, 2005)
Andrographolide is a bicyclic diterpenoid lactone derived from extracts of Andrographis paniculata, a plant indigenous to South Asian countries that shows anti-inflammatory properties. The molecular and cellular bases for ...