FK506-binding proteins are members of the immunophilin family of proteins. Those immunophilins associated to the 90-kDa-heat-shock protein, Hsp90, have been proposed as potential modulators of signalling cascade factors ...

Immunophilins comprise a family of proteins characterized by the presence of a specific sequence that usually shows peptidyl‐prolyl‐(cis/trans )‐isomerase (PPIase) activity, i.e., the reversible cis/trans interconversion ...

Immunophilins are a family of intracellular receptors for immunosuppressive drugs. Those immunophilins that are related to immunosuppression are the smallest proteins of the family, i.e., FKBP12 and CyPA, whereas the other ...

The term immunophilin involves a family of proteins whose signature domain shows peptidyl-prolyl-(cis/trans)-isomerase (PPIase) enzymatic activity, i.e., the reversible cis/trans interconversion of Xaa-Pro bonds (Erlejman ...

Es sabido que el movimiento de proteínas englobadas en vesículas utiliza al citoesqueleto como vías de transporte. Sin embargo, nada se sabe acerca del mecanismo de transporte de proteínas solubles no asociadas a vesículas. ...

The biological function of proteins is determined by their cellular localization and subsequent interactions with other factors within a given subcellular compartment. Therefore, it is critical to understand how proteins ...

Introduction : Injuries in peripheral nerves are common in clinical practice being responsible for serious problems and often permanent as loss of motor, sensitive functions, acute and chronic pain. Although surgical, ...

Introduction : Injuries in peripheral nerves are common in clinical practice being responsible for serious problems and often permanent as loss of motor, sensitive functions, acute and chronic pain. Although surgical, ...