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Infection with Trypanosoma cruzi restricts the repertoire of parasite-specific CD8(+) T cells leading to immunodominance
(American Association of Immunologists, 2023)
Obtaining immunodominant fractions of Leishmania antigens to compose an intranasal vaccine against Leishmania (Viannia) braziliensis infection in the hamster model
(Fiocruz/Instituto de Tecnologia em Imunobiológicos, 2019)
Identification of immunodominant proteins from the Viannia and Leishmania subgenera for the composition of a pan vaccine specific for leishmaniasis
(Fiocruz/Instituto de Tecnologia em Imunobiológicos, 2022)
Immunodominance: a new hypothesis to explain parasite escape and host/parasite equilibrium leading to the chronic phase of Chagas' disease?
(Associação Brasileira de Divulgação Científica, 2009-03-01)
Intense immune responses are observed during human or experimental infection with the digenetic protozoan parasite Trypanosoma cruzi. The reasons why such immune responses are unable to completely eliminate the parasites ...
Mapping of B cell epitopes in an immunodominant antigen of Trypanosoma cruzi using fusions to the Escherichia coli LamB protein
(Elsevier B.V., 1998-07-01)
The JL8 protein antigen from Trypanosoma cii , a dominant immunogen in man, has been characterized as containing tandem amino acid repeats. Here, we describe the use of the LamB protein of Escherichia coli as a carl icr ...
Cloning and characterization of a gene encoding a novel immunodominant antigen of Trypanosoma cruzi
(Elsevier B.V., 1997-08-01)
A Trypanosoma cruzi genomic expression library was screened with a pool of sera obtained from chronic chagasic patients. the recombinant antigen (Tc40) isolated from this library reacted with a large number of serum samples ...
DETECTION of ANTIBODIES in SERA FROM CHAGAS-DISEASE PATIENTS USING A TRYPANOSOMA-CRUZI IMMUNODOMINANT RECOMBINANT ANTIGEN
(Blackwell Science Ltd, 1994-03-01)
A Trypanosoma cruzi DNA fragment encoding an immunodominant repetitive antigen (H49) was subcloned into a protein purification and expressed system. Purified H49 peptide reacted specifically in an enzyme-linked immunosorbent ...