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A novel high-throughput assay for islet respiration reveals uncoupling of rodent and human islets
(Public Library of Science (PLoS), 2012-05)
The pancreatic beta cell is unique in its response to nutrient by increased fuel oxidation. Recent studies have demonstrated that oxygen consumption rate (OCR) may be a valuable predictor of islet quality and long term ...
Increased pancreatic islet mass is accompanied by activation of the insulin receptor substrate-2/serine-threonine kinase pathway and augmented cyclin D(2) protein levels in insulin-resistant rats
(Wiley-Blackwell, 2008-08-01)
It is well known that glucocorticoids induce peripheral insulin resistance in rodents and humans. Here, we investigated the structural and ultrastructural modifications, as well as the proteins involved in beta-cell function ...
Increased pancreatic islet mass is accompanied by activation of the insulin receptor substrate-2/serine-threonine kinase pathway and augmented cyclin D(2) protein levels in insulin-resistant rats
(Wiley-Blackwell, 2008-08-01)
It is well known that glucocorticoids induce peripheral insulin resistance in rodents and humans. Here, we investigated the structural and ultrastructural modifications, as well as the proteins involved in beta-cell function ...
Islet Cannabinoid Receptors Cellular Distribution and Biological Function
(Lippincott, Williams, 2013-10)
Objectives: To determine the cellular distribution of islet cannabinoid receptors (CBs) and their involvement in the development of metabolic and hormonal changes in rats fed a fructose-rich diet (F). Methods: In normal ...
Neurogenin 3 is important but not essential for pancreatic islet development in humans
(Springer Verlag, 2014)
Pancreatic islet transplantation
(2009-09-21)
Abstract
Background
No formulation of exogenous insulin available to date has yet been able to mimic the physiological nictemeral rhythms of this hormone, and despite all ...
Pancreatic islet transplantation
(2009-09-21)
Abstract
Background
No formulation of exogenous insulin available to date has yet been able to mimic the physiological nictemeral rhythms of this hormone, and despite all ...
Expression of PDX-1 is reduced in pancreatic islets from pups of rat dams fed a low protein diet during gestation and lactation
(Amer Inst NutritionBethesdaEUA, 2002)