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Functional Ca2+ Channels between Channel Clusters are Necessary for the Propagation of IP3R-Mediated Ca2+ Waves
(Multidisciplinary Digital Publishing Institute, 2019-06-11)
The specificity and universality of intracellular Ca2+ signals rely on the variety of spatio-temporal patterns that the Ca2+ concentration can display. Ca2+ release into the cytosol through inositol 1,4,5-trisphosphate ...
Converged networksRedes convergentes
(Universidad Militar Nueva Granada, 2004)
Changes in Ca2+ removal can mask the effects of geometry during IP3R mediated Ca2+ signals
(Frontiers Media, 2019-07-31)
Calcium (Ca2+) signals are ubiquitous. Most intracellular Ca2+ signals involve the release of Ca2+ from the endoplasmic reticulum (ER) through Inositol 1,4,5-Trisphosphate Receptors (IP3Rs). The non-uniform spatial ...
Luminal Ca 2+ dynamics during IP 3 R mediated signals
(IOP Publishing, 2016-05)
The role of cytosolic Ca2+ on the kinetics of Inositol 1,4,5-triphosphatereceptors (IP3Rs) and on the dynamics of IP3R-mediated Ca2+ signals has been studiedat large both experimentally and by modeling. The role of luminal ...
The inositol trisphosphate receptor in the control of autophagy
(LANDES BIOSCIENCE, 2007-07)
The second messenger myo-inositol-1,4,5-trisphosphate (IP3) acts on the IP3 receptor (IP3R), an IP3-activated Ca2+ channel of the endoplasmic reticulum (ER). The IP3R agonist IP3 inhibits starvation-induced autophagy. The ...
Abnormal distribution of inositol 1,4,5-trisphosphate receptors in human muscle can be related to altered calcium signals and gene expression in Duchenne dystrophy-derived cells
(2010)
Inositol 1,4,5-trisphosphate (IP3) receptors (IP3Rs) drive calcium signals involved in skeletal muscle excitation-transcription coupling and plasticity; IP3R subtype distribution and downstream events evoked by their ...