The specific role of the chloride anion (Cl−) as a signalling effector or second messenger has been increasingly recognized in recent years. It could represent a key factor in the regulation of cellular homeostasis. Changes ...

Mammalian cells have a large number of intracellular peptides that are generated by extralysosomal proteases. In this study, the enzymatic activity of thimet oligopeptidase (EP24.15) was inhibited in human embryonic kidney ...

Classically, receptors were defined as cellular structures that recognize and bind hormones. In present days this definition is expanded to include receptors for a variety of other extracellular regulatory signaling ...