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Infection Strategies of Intestinal Parasite Pathogens and Host Cell Responses
(Frontiers Media Sa, 2016)
Giardia lamblia, Cryptosporidium sp., and Entamoeba histolytica are important pathogenic intestinal parasites and are amongst the leading causes worldwide of diarrheal illness in humans. Diseases caused by these organisms, ...
Oral co-administration of a bacterial protease inhibitor in the vaccine formulation increases antigen delivery at the intestinal epithelial barrier
(Elsevier Science, 2019-01)
The study of capture and processing of antigens (Ags) by intestinal epithelial cells is very important for development of new oral administration systems. Efficient oral Ag delivery systems must resist enzymatic degradation ...
Physiological and pathophysiological factors affecting the expression and activity of the drug transporter MRP2 in intestine: Impact on its function as membrane barrier
(Academic Press Ltd - Elsevier Science Ltd, 2016-07)
The gastrointestinal epithelium functions as a selective barrier to absorb nutrients, electrolytes and water, but at the same time restricts the passage into the systemic circulation of intraluminal potentially toxic ...
Oral administration of probiotics increases paneth cells and intestinal antimicrobial activity
(Frontiers Media SA, 2018-04-16)
The huge amount of intestinal bacteria represents a continuing threat to the intestinal barrier. To meet this challenge, gut epithelial cells produce antimicrobial peptides (AMP) that act at the forefront of innate immunity. ...
Intervenções não farmacológicas para a redução do peso melhoram ou não a condição da barreira intestinal?
(Universidade Federal do Rio Grande do NorteBrasilUFRNNutriçãoNutrição, 2023)
Intraluminal nutrients acutely strengthen rat intestinal MRP2 barrier function by a glucagon-like peptide-2-mediated mechanism
(Wiley Blackwell Publishing, Inc, 2020-06)
Aim: MRP2 is an intestinal ABC transporter that prevents the absorption of dietary xenobiotics. The aims of this work were: (1) to evaluate whether a short-term regulation of intestinal MRP2 barrier function takes place ...