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Cytokine inhibition and time-related influence of inflammatory stimuli on the hyperalgesia induced by the nucleus pulposus
(SPRINGERNEW YORK, 2012)
The symptoms of lumbar disc herniation, such as low back pain and sciatica, have been associated with local release of cytokines following the inflammatory process induced by the contact of the nucleus pulposus (NP) with ...
5-HT acts on nociceptive primary afferents through an indirect mechanism to induce hyperalgesia in the subcutaneous tissue
(Pergamon-elsevier Science LtdOxfordInglaterra, 2007)
Peripheral mechanisms underlying the essential role of P2X7 receptors in the development of inflammatory hyperalgesia
(Elsevier Science BvAmsterdamHolanda, 2010)
Magnesium sulfate prevents the development of forced swim induced hyperalgesia in rats
(Universidad del Zulia, 2018)
Nerve growth factor acts with the beta 2-adrenoceptor to induce spontaneous nociceptive behavior during temporomandibular joint inflammatory hyperalgesia
(Pergamon-elsevier Science LtdOxfordInglaterra, 2008)
Impact of sex on hyperalgesia induced by sleep loss
(Elsevier B.V., 2011-01-01)
This study evaluated the impact of sex on the short term consequences of different periods of sleep deprivation and the effect of the respective sleep recovery periods on nociceptive responses. Male and female C57BL/6J ...
The C-terminus of murine S100A9 protein inhibits hyperalgesia induced by the agonist peptide of protease-activated receptor 2 (PAR(2))
(Nature Publishing Group, 2006-10-01)
Background and purpose: S100A9 protein induces anti-nociception in rodents, in different experimental models of inflammatory pain. Herein, we investigated the effects of a fragment of the C-terminus of S100A9 (mS100A9p), ...
The use of kinin B-1 and B-2 receptor knockout mice and selective antagonists to characterize the nociceptive responses caused by kinins at the spinal level
(Elsevier B.V., 2002-12-01)
The mechanisms by which kinins induce hyperalgesia in the spinal cord were investigated by using B-1 or B-2 knockout mice in conjunction with kinin selective agonists and antagonists. the i.t. administration of the kinin ...
Hydrogen peroxide is a novel mediator of inflammatory hyperalgesia, acting via transient receptor potential vanilloid 1-dependent and independent mechanisms
(ELSEVIER SCIENCE BV, 2009)
Inflammatory diseases associated with pain are often difficult to treat in the clinic due to insufficient understanding of the nociceptive pathways involved. Recently, there has been considerable interest in the role of ...