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Biological and clinical impact of imbalanced progesterone receptor isoform ratios in breast cancer
(BioScientifica, 2018-12)
There is a consensus that progestins and thus their cognate receptor molecules, the progesterone receptors (PRs), are essential in the development of the adult mammary gland and regulators of proliferation and lactation. ...
Histamine H4 receptor : insights into a potential therapeutic target in breast cancer
(2015)
Abstract: Breast cancer is the second most common cancer worldwide, and the leading cause of cancer
death in women. Several studies underlined the critical role of histamine in breast cancer development and
progression. ...
Efeito de um complexo de rutênio em células de câncer de mama em diferentes modelos 2D e 3D in vitro e in vivo
(Universidade Federal de São CarlosUFSCarPrograma Interinstitucional de Pós-Graduação em Ciências Fisiológicas - PIPGCFCâmpus São Carlos, 2019-10-18)
Cancer is among the leading causes of morbidity and mortality in the world. Specifically, breast cancer is an extremely heterogeneous disease, being composed of different subtypes and this heterogeneity makes treatment ...
Stimuli-responsive drug delivery nanocarriers in the treatment of breast cancer
(2020-01-01)
Stimuli-responsive drug-delivery nanocarriers (DDNs) have been increasingly reported in the literature as an alternative for breast cancer therapy. Stimuli-responsive DDNs are developed with materials that present a drastic ...
Combined photodynamic therapy with chloroaluminum phthalocyanine and doxorubicin nanoemulsions in breast cancer model
(Elsevier B.V., 2021-05-01)
Breast cancer is the most common neoplasm among women but thanks to innovative therapies, patients' prognosis has considerably improved. In this aspect, nanotechnology has been applied for cancer therapy aiming to reduce ...
Avaliação da atividade antitumoral in vitro e in vivo de novos complexos de rutênio contendo ácido salicílico e derivados
(Universidade Federal de São CarlosUFSCarPrograma Interinstitucional de Pós-Graduação em Ciências Fisiológicas - PIPGCFCâmpus São Carlos, 2021-04-30)
Cancer is a term used for diseases in which abnormal cells divide uncontrolled, spread, and invade other tissues through the blood and lymphatic systems. Breast cancer is one of the most common and with higher mortality ...
Milk fermented by Lactobacillus casei CRL431 administered as an immune adjuvant in models of breast cancer and metastasis under chemotherapy
(Springer, 2021-01)
Chemotherapy is the most common treatment for breast cancer and its metastasis; however, it affects the patients' quality of life. Previously, it was demonstrated that milk fermented by Lactobacillus casei CRL431 (probiotic ...
Targeting FGFR with BGJ398 in breast cancer: Effect on tumor growth and metastasis
(Bentham Science Publishers, 2017-12)
AbstractBACKGROUND:Endocrine resistance and metastatic dissemination comprise major clinical challenges for breast cancer treatment. The fibroblast growth factor receptor family (FGFR) consists of four tyrosine kinase ...
Metformin and propranolol combination prevents cancer progression and metastasis in different breast cancer models
(Impact Journals LLC, 2017-01)
Discovery of new drugs for cancer treatment is an expensive and time-consuming process and the percentage of drugs reaching the clinic remains quite low. Drug repositioning refers to the identification and development of ...
In vivo and in vitro estrogenic and progestagenic actions of Tibolone
(Sociedad de Biología de Chile, 2005)