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Capillary bioreactors based on human purine nucleoside phosphorylase: A new approach for ligands identification and characterization
(ELSEVIER SCIENCE BVAMSTERDAM, 2012)
The enzyme purine nucleoside phosphorylase (PNP) is a target for the discovery of new lead compounds employed on the treatment severe T-cell mediated disorders. Within this context, the development of new, direct, and ...
Structure of human PNP complexed with ligands
(Blackwell Publishing, 2005-07-01)
Purine nucleoside phosphorylase (PNP) is a key enzyme in the purine-salvage pathway, which allows cells to utilize preformed bases and nucleosides in order to synthesize nucleotides. PNP is specific for purine nucleosides ...
Structure of human PNP complexed with ligands
(Blackwell Publishing, 2005-07-01)
Purine nucleoside phosphorylase (PNP) is a key enzyme in the purine-salvage pathway, which allows cells to utilize preformed bases and nucleosides in order to synthesize nucleotides. PNP is specific for purine nucleosides ...
Structure of human PNP complexed with ligands
(Blackwell Publishing, 2014)