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Topical interleukin-1 receptor antagonist inhibits inflammatory cell infiltration into the cornea
(ACADEMIC PRESS LTD ELSEVIER SCIENCE LTD, 2008)
Interleukin (IL)-1 alpha and beta are important modulators of many functions of corneal epithelial and stromal cells that occur following injury to the cornea, including the influx of bone marrow-derived inflammatory cells ...
Rethinking interleukin-6 blockade for treatment of COVID-19
Interleukin-6 (IL-6) is a pleiotropic cytokine with effects in immune regulation, inflammation, and infection. The
use of drugs that inhibit IL-6 biological activity has been proposed as a treatment for patients with ...
Role of testosterone and androgen receptor in periodontal disease progression in female rats
(2020-04-01)
Background: Sex hormone therapy has strict recommendations in the treatment of postmenopausal symptoms, in which testosterone (TES) replacement may play a potential role. However, it remains unclear whether TES affects the ...
Association between mannose-binding lectin and interleukin-1 receptor antagonist gene polymorphisms and recurrent vulvovaginal candidiasis
(SPRINGER HEIDELBERGHEIDELBERG, 2012)
Objective The influence of functional polymorphisms in the genes coding for mannose-binding lectin (MBL) and interleukin-1 receptor antagonist (IL-1ra) on recurrent vulvovaginal candidiasis (RVVC) were examined in an urban ...
Maternal and neonatal interleukin-1 receptor antagonist genotype and pregnancy outcome in a population with a high rate of pre-term birth
(WILEY-BLACKWELL, 2008)
Problem We evaluated associations between a length polymorphism in intron 2 of the gene coding for IL-1ra (gene symbol IL1RN) and pregnancy outcome in a population with a high rate of preterm birth. Method of study Subjects ...
The role of androgens on periodontal repair in female rats
(Amer Acad Periodontology, 2018-04-01)
Background: Testosterone replacement enhances cognitive function and musculoskeletal health in postmenopausal women. However, the biological role of testosterone on inflammation and bone metabolism in females is not well ...
Endocannabinoids, Through Opioids And Prostaglandins, Contribute To Fever Induced By Key Pyrogenic Mediators
(ACADEMIC PRESS INC ELSEVIER SCIENCESAN DIEGO, 2016)
Androgen receptors and experimental bone loss - an in vivo and in vitro study
(Elsevier B. V., 2015)
Testosterone is a sex hormone that exhibits many functions beyond reproduction; one such function is the regulation of bone metabolism. The role played by androgen receptors during testosterone-mediated biological processes ...