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IFNG +874 T>A single nucleotide polymorphism is associated with leprosy among Brazilians
(Springer Verlag (Germany), 2018)
Clinical healing of antimony - resistant cutaneous or mucocutaneous Leishmaniasis following the combined administration of IFN-g and pentavalent antimonials (Sb v)
(Acta Andina, 1993)
In a phase II open trial, combined therapy with SbV (10mg/kg body weight), and recombinant human IFN-g (100 µg/m2 body surface area), was administered to 13 patients with diagnosis of cutaneous or mucocutaneous leishmaniasis, ...
IFNG-mediated immune responses enhance autophagy against Mycobacterium tuberculosis antigens in patients with active tuberculosis
(Landes Bioscience, 2014-11)
Protective immunity against Mycobacterium tuberculosis (Mtb) requires IFNG. Besides, IFNG-mediated induction of autophagy suppresses survival of virulent Mtb in macrophage cell lines. We investigated the contribution of ...
Normal expression of IFN-gR in four patients with uncommon mycobacterial infection phenotypes
(2004)
Several primary immunodeficiency diseases affecting the interleukin 12/interferon gamma (IFN-g) pathway have been identified, most of them characterized by recurrent and protracted infections produced by intracellular ...
Evaluation of IFN-g and TNF-a as immunological markers of clinical outcome in cutaneous leishmaniasis
(2002)
Para avaliar se os níveis séricos de IFN-g e TNF-a podem ser usados como marcadores da resposta terapêutica na leishmaniose cutânea, 54 pacientes com história de uma única lesão ulcerada com duração de até 30 dias foram ...
The Impact of IFN-g; Receptor on SLPI Expression in Active Tuberculosis: Association with Disease Severity
(Amer Soc Investigative Pathology, Inc, 2014-05)
Interferon (IFN)-g displays a critical role in tuberculosis (TB), modulating the innate and adaptive immune responses. Previously, we reported that secretory leukocyte protease inhibitor (SLPI) is a pattern recognition ...
Presence of Circulating Levels of Interferon-g, Interleukin-10 and Tumor Necrosis Factor-a in Patients with Visceral Leishmaniasis
(Instituto de Medicina Tropical, 1998-01-01)
Experimental murine L. major infection is characterized by the expansion of distinct CD4+ T cell subsets. The Th1 response is related to production of IFN-g and resolution of infection, whereas Th-2 response with production ...