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Biochemical study of idebenone effect on mitochondrial metabolism of yeast
(Academic Press Ltd - Elsevier Science Ltd, 2008-12)
The aim of this work was to study the effect of the drug idebenone on the growth of a strain of Saccharomyces cerevisiae yeast and its respiratory-deficient mutant (rho0). We took this yeast as a model system of the ...
Effect of the antioxidant idebenone on maternal diabetes-induced embryo alterations during early organogenesis
(Reproductive Healthcare Ltd, 2018-10)
Research question: Can maternal treatments with idebenone, a structural analogue of coenzyme Q10, prevent alterations on markers of proinflammatory–prooxidant processes, on the expression of genes involved in mitochondrial ...
Desenvolvimento tecnológico de suspensões e liofilizados de nanocápsulas poliméricas para a veiculação do neuroprotetor idebenona
(Universidade Federal de Santa MariaBRFarmáciaUFSMPrograma de Pós-Graduação em Ciências Farmacêuticas, 2013-10-30)
Idebenone is an antioxidant, a synthetic derivative of coenzyme Q10, with several applications, such as neuroprotection. However, this drug has low solubility in water, besides is irritant substance and has chemical ...
Pro-oxidant/pro-inflammatory alterations in the offspring´s heart of mild diabetic rats are regulated by maternal treatments with a mitochondrial antioxidant
(Pergamon-Elsevier Science Ltd, 2017-10)
Maternal diabetes programs metabolic and cardiovascular diseases in the offspring. Here, we demonstrated increased pro-oxidant/pro-inflammatory markers in the heart of 2-day-old offspring of diabetic rats, previous to the ...
Dentate Nuclei T2 Relaxometry Is A Reliable Neuroimaging Marker In Friedreich's Ataxia
(Blackwell Publishing Ltd, 2014)
Efecto de las propiedades estructurales de la partícula sobre la liberación de moléculas encapsuladas en sistemas lipídicos coloidales
(Bogotá - Ciencias - Doctorado en Ciencias FarmacéuticasDepartamento de FarmaciaUniversidad Nacional de Colombia - Sede Bogotá, 2020-01-16)
Las nanopartículas sólidas lipídicas (SLN) y los transportadores lipídicos nanoestructurados (NLC) han atraído la atención durante más de dos décadas como una alternativa para la entrega de fármacos poco solubles en agua. ...