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A short hairpin RNA-based adjuvant targeting NF-kappa B repressor I kappa B alpha promotes migration of dermal dendritic cells to draining lymph nodes and antitumor CTL responses induced by DNA vaccination
(Elsevier, 2017)
DNA vaccination is an attractive approach to elicit tumor-specific cytotoxic CD8(+) T lymphocytes (CTL), which can mediate protective immunity against tumors. To initiate CTL responses, antigen-encoding plasmids employed ...
Insulin suppresses LPS-induced iNOS and COX-2 expression and NF-kappa B activation in alveolar macrophages
(KARGER, 2008)
The development of septic shock is a common and frequently lethal consequence of gram-negative infection. Mediators released by lung macrophages activated by bacterial products such as lipopolysaccharide (LPS) contribute ...
Effects of Protein-Energy Malnutrition on NF-KappaB Signalling in Murine Peritoneal Macrophages
(SPRINGER/PLENUM PUBLISHERS, 2010)
Protein-energy malnutrition (PEM) is an important public health problem affecting millions of people worldwide. PEM decreases resistance to infection, impairing a number of physiological processes. In unstimulated cells, ...
Tumor necrosis factor-alpha activates nuclear factor-kappa B but does not regulate progesterone production in cultured human granulosa luteal cells
(PARTHENON PUBLISHING GROUP, 2007-07)
Background. The role of tumor necrosis factor-alpha (TNF-alpha) in granulosa luteal cell function and steroidogenesis is still controversial. Our aim was to examine the steroiclogenic response, together with the simultaneous ...
Hippocampal dynamics of synaptic NF-kappa B during inhibitory avoidance long-term memory consolidation in mice
(Pergamon-Elsevier Science Ltd, 2015-04)
Since the discovery that long-term memory is dependent on protein synthesis, several transcription factors have been found to participate in the transcriptional activity needed for its consolidation. Among them, NF-kappa ...
Effects of glutamine on the nuclear factor-kappaB signaling pathway of murine peritoneal macrophages
(SPRINGER, 2010)
The aim of this study was to evaluate the effect of glutamine on the expression of proteins involved in the nuclear factor-kappaB (NF-kappa B) signaling pathway of murine peritoneal macrophages. Since glutamine is essential ...
Halothane induces oxidative stress and NF-kappa B activation in rat liver: Protective effect of propofol
(Elsevier B.V., 2006-10-03)
We investigated the effects of propofol on markers of oxidative stress, nuclear factor kappa B (NF-kappa B) activation and inducible nitric oxide synthase (NOS) expression in liver of rats treated with halothane under ...
Hyperosmotic stress activates p65/RelB NF kappa B in cultured cardiomyocytes with dichotomic actions on caspase activation and cell death
(ELSEVIER, 2006-06-12)
NF kappa B is a participant in the process whereby cells adapt to stress. We have evaluated the activation of NF kappa B pathway by hyperosmotic stress in cultured cardiomyocytes and its role in the activation of caspase ...
Thyroid hormone-induced oxidative stress in rodents and humans: A comparative view and relation to redox regulation of gene expression
(ELSEVIER, 2006-04)
Thyroid hormone (3,3',5-triiodothyronine, T-3) exerts significant actions on energy metabolism, with mitochondria being the major target for its calorigenic. effects. Acceleration of O-2 consumption by T-3 leads to ail ...