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Ghrelin Indirectly Activates Hypophysiotropic CRF Neurons in Rodents
(Public Library of Science, 2012-02)
Ghrelin is a stomach-derived hormone that regulates food intake and neuroendocrine function by acting on its receptor, GHSR (Growth Hormone Secretagogue Receptor). Recent evidence indicates that a key function of ghrelin ...
Physiology, molecular biology and therapeutic potential of the thymic peptide thymulin
(Sociedad Argentina de Fisiología, 2012-10)
Thymulin is a thymic hormone exclusively produced by the thymic epithelial cells. After its discovery and initial characterization in the ‘70s, it was demonstrated that thymulin production and secretion is strongly influenced ...
Ghrelin activates hypophysiotropic corticotropin-releasing factor neurons independently of the arcuate nucleus
(Pergamon-Elsevier Science Ltd, 2016-05)
Previous work has established that the hormone ghrelin engages the hypothalamic-pituitary-adrenal neuroendocrine axis via activation of corticotropin-releasing factor (CRF) neurons of the hypothalamic paraventricular nucleus ...
Conservation of three-dimensional helix-loop-helix structure through the vertebrate lineage reopens the cold case of gonadotropin-releasing hormone-associated Peptide
(Frontiers Research Foundation, 2017-08)
GnRH-associated peptide (GAP) is the C-terminal portion of the gonadotropin-releasing hormone (GnRH) preprohormone. Although it was reported in mammals that GAP may act as a prolactin-inhibiting factor and can be co-secreted ...
Physiology and Therapeutic Potential of the Thymic Peptide Thymulin
(Bentham Science Publishers, 2014-07)
Thymulin is a thymic hormone exclusively produced by the epithelial cells of the thymus. After its discovery and initial characterization in the ‘70s, it was demonstrated that the production and secretion of thymulin are ...