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A study about regioisomeric hydroquinones with multiple intramolecular hydrogen bonding
(MDPI AG, 2017)
A theoretical exploration about hydrogen bonding in a series of synthetic regioisomeric antitumor tricyclic hydroquinones is presented. The stabilization energy for the intramolecular hydrogen bond (IHB) formation in four ...
Assessing parameter suitability for the strength evaluation of intramolecular resonance assisted hydrogen bonding in O-carbonyl hydroquinones
(MDPI AG, 2019)
© 2019 by the authors.Intramolecular hydrogen bond (IMHB) interactions have attracted considerable attention due to their central role in molecular structure, chemical reactivity, and interactions of biologically active ...
Intramolecular hydrogen bond in biologically active o-carbonyl hydroquinones
(MDPI, 2014)
Intramolecular hydrogen bonds (IHBs) play a central role in the molecular
structure, chemical reactivity and interactions of biologically active molecules. Here, we
study the IHBs of seven related o-carbonyl hydroquinones ...
Intramolecular Hydrogen Bond in Biologically Active o-Carbonyl Hydroquinones
(MDPI AG, POSTFACH, 2014)
Synthesis of antiplatelet ortho-carbonyl hydroquinones with differential action on platelet aggregation stimulated by collagen or TRAP-6
(Elsevier, 2020)
Cardiovascular diseases are the leading cause of death in the world. Platelets have a major role in cardiovascular events as they bind to the damaged endothelium activating and forming thrombi. Although some hydroquinone ...
Studies on quinones. Part 39: Synthesis and leishmanicidal activity of acylchloroquinones and hydroquinones
(PERGAMON-ELSEVIER SCIENCE LTD, 2005)
Acylhydroquinone-based compounds are attractive targets for the design of new leishmanicidal drugs. We have previously described sesquiterpene quinones and hydroquinones series, which exhibit different degree of potency ...
Small structural changes on a hydroquinone scaffold determine the complex I inhibition or uncoupling of tumoral oxidative phosphorylation
(Academic Press Elsevier Science, 2016)
Mitochondria participate in several distinctiveness of cancer cell, being a promising target for the design of anti-cancer compounds. Previously, we described that ortho-carbonyl hydroquinone scaffold 14 inhibits the complex ...
Electrochemical characterization of hydroquinone derivatives with different substituents in acetonitrile
(Royal Soc Chemistry, 2015)
The effect of carbonyl groups in the ortho position with respect to a hydroxyl group on the electrochemical oxidation of hydroquinones in acetonitrile is studied. The electrochemical response of hydroquinone on a glassy ...
In vitro activity of compounds isolated from Piper crassinervium against Trypanosoma cruzi
(Taylor & Francis Ltd, 2008-01-01)
This study describes the antichagasic potential of five compounds isolated from leaves of Piper crassinervium (Piperaceae). Two prenylated benzoic acid derivatives, one prenylated hydroquinone and two flavanones, were ...
In vitro activity of compounds isolated from Piper crassinervium against Trypanosoma cruzi
(Taylor & Francis Ltd, 2008-01-01)
This study describes the antichagasic potential of five compounds isolated from leaves of Piper crassinervium (Piperaceae). Two prenylated benzoic acid derivatives, one prenylated hydroquinone and two flavanones, were ...