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Complexation of 2-acetylpyridine- and 2-benzoylpyridine-derived hydrazones to copper(II) as an effective strategy for antimicrobial activity improvement

Recio Despaigne, Angel A.; Da Costa, Fernanda B.; Piro, Oscar Enrique; Castellano, Eduardo E.; Louro, Sonia R.W.; Beraldo, Heloisa (Pergamon-Elsevier Science Ltd, 2012-03)

Complexes [Cu(2AcPh)Cl]·2H 2O (1), [Cu(2AcpClPh)Cl] ·2H 2O (2), [Cu(2AcpNO 2Ph)Cl] (3), [Cu(2BzPh)Cl] (4). [Cu(2BzpClPh)Cl] (5) and [Cu(2BzpNO 2Ph)Cl] (6) were obtained with 2-acetylpyridine-phenylhydrazone (H2AcPh), ...

Copper(II) and zinc(II) complexes with 2-formylpyridine-derived hydrazones

DESPAIGNE, Angel A. Recio; SILVA, Jeferson G. da; CARMO, Ana Cerulia M. do; SIVES, Flavio; PIRO, Oscar E.; CASTELLANO, Eduardo Ernesto; BERALDO, Heloisa (PERGAMON-ELSEVIER SCIENCE LTD, 2009)

In the present work 2-formylpyridine-para-chloro-phenyl hydrazone (H2FopCIPh) and 2-formylpyridine-para-nitro-phenyl hydrazone (H2FopNO(2)Ph) were obtained, as well as their copper(II) and zinc(II) complexes [Cu(H2FopClPh)Cl(2)] ...

Pharmacological evaluation and preparation of nonsteroidal anti-inflammatory drugs containing an N-Acyl hydrazone subunit

Universidade Estadual Paulista (Unesp)|Universidade de São Paulo (USP) (2014)

A series of anti-inflammatory derivatives containing an N-acyl hydrazone subunit (4a–e) were synthesized and characterized. Docking studies were performed that suggest that compounds 4a–e bind to cyclooxygenase (COX)-1 and ...

Pharmacological Evaluation and Preparation of Nonsteroidal Anti-Inflammatory Drugs Containing an N-Acyl Hydrazone Subunit

Universidade Estadual Paulista (Unesp); Universidade de São Paulo (USP) (Mdpi Ag, 2014-04-01)

A series of anti-inflammatory derivatives containing an N-acyl hydrazone subunit (4a-e) were synthesized and characterized. Docking studies were performed that suggest that compounds 4a-e bind to cyclooxygenase (COX)-1 and ...

Analgesic and anti-inflammatory activities of salicylaldehyde 2-chlorobenzoyl hydrazone (H2LASSBio-466), salicylaldehyde 4-chlorobenzoyl hydrazone (H 2LASSBio-1064) and their zinc(II) complexes

Júnior, Walfrido Bispo; Alexandre Moreira, Magna S.; Alves, Marina A.; Pérez Rebolledo, Anayive; Parrilha, Gabrieli L.; Castellano, Eduardo Ernesto; Piro, Oscar Enrique; Barreiro, Eliezer Jesus de Lacerda; Lima, Lídia Moreira; Beraldo, Heloisa (2011)

Vanadium complexes with hydrazone or thiosemicarbazone ligands as potential anti-mycobacterium tuberculosis agents

Universidade Estadual Paulista (Unesp); Universidade de São Paulo (USP) (Bentham Science Publishers, 2015)

Tuberculosis (TB) is an infectious disease caused mainly by Mycobacterium tuberculosis (MTB) and still an important public health problem worldwide. Some factors like the emergence of multidrug resistant (MDR) and extensively ...

2-Acetylpyridine- and 2-benzoylpyridine-derived hydrazones and their gallium(III) complexes are highly cytotoxic to glioma cells

Despaigne, Angel A. R.; Parrilha, Gabrieli L.; Izidoro, Jans B.; da Costa, Pryscila R.; dos Santos, Raquel G.; Piro, Oscar E.; Castellano, Eduardo Ernesto; Rocha, Willian R.; Beraldo, Heloisa (ELSEVIER FRANCE-EDITIONS SCIENTIFIQUES MEDICALES ELSEVIERPARIS, 2012)

2-Acetylpyridine-phenylhydrazone (H2AcPh), its para-chlorophenylhydrazone (H2AcpClPh) and para-nitrophenylhydrazone (H2AcpNO(2)Ph) analogues, the corresponding 2-benzoylpyridine-derived hydrazones (H2BzPh, H2BzpClPh and ...

Synthesis, Spectroscopic Characterizations, Crystal Structures And Dft Studies Of Nalidixic Acid Carbonyl Hydrazones Derivatives

Bergamini; F. R. G.; Ribeiro; M. A.; Lancellotti; M.; Machado; D.; Miranda; P. C. M. L.; Cuin; A.; Formiga; A. L. B.; Corbi; P. P. (Elsevier Science BVAmsterdam, 2016)

Synthesis, Spectroscopic Characterizations, Crystal Structures And Dft Studies Of Nalidixic Acid Carbonyl Hydrazones Derivatives

Bergamini; FRG; Ribeiro; MA; Lancellotti; M; Machado; D; Miranda; PCML; Cuin; A; Formiga; ALB; Corbi; PP (ELSEVIER SCIENCE BVAMSTERDAM, 2016)

Design, synthesis and anti-tuberculosis activity of hydrazones and n-acylhydrazones containing vitamin B6 and different heteroaromatic nucleus

Nogueira, Thais Cristina Mendonça; Cruz, Lucas dos Santos; Lourenço, Maria Cristina; Souza, Marcus Vinicius Nora de (Bentham Science Publishers, 2019)

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Complexation of 2-acetylpyridine- and 2-benzoylpyridine-derived hydrazones to copper(II) as an effective strategy for antimicrobial activity improvement

Copper(II) and zinc(II) complexes with 2-formylpyridine-derived hydrazones

Pharmacological evaluation and preparation of nonsteroidal anti-inflammatory drugs containing an N-Acyl hydrazone subunit

Pharmacological Evaluation and Preparation of Nonsteroidal Anti-Inflammatory Drugs Containing an N-Acyl Hydrazone Subunit

Analgesic and anti-inflammatory activities of salicylaldehyde 2-chlorobenzoyl hydrazone (H2LASSBio-466), salicylaldehyde 4-chlorobenzoyl hydrazone (H 2LASSBio-1064) and their zinc(II) complexes

Vanadium complexes with hydrazone or thiosemicarbazone ligands as potential anti-mycobacterium tuberculosis agents

2-Acetylpyridine- and 2-benzoylpyridine-derived hydrazones and their gallium(III) complexes are highly cytotoxic to glioma cells

Synthesis, Spectroscopic Characterizations, Crystal Structures And Dft Studies Of Nalidixic Acid Carbonyl Hydrazones Derivatives

Synthesis, Spectroscopic Characterizations, Crystal Structures And Dft Studies Of Nalidixic Acid Carbonyl Hydrazones Derivatives

Design, synthesis and anti-tuberculosis activity of hydrazones and n-acylhydrazones containing vitamin B6 and different heteroaromatic nucleus