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Pharmacological evaluation and preparation of nonsteroidal anti-inflammatory drugs containing an N-Acyl hydrazone subunit
(2014)
A series of anti-inflammatory derivatives containing an N-acyl hydrazone subunit (4a–e) were synthesized and characterized. Docking studies were performed that suggest that compounds 4a–e bind to cyclooxygenase (COX)-1 and ...
Pharmacological Evaluation and Preparation of Nonsteroidal Anti-Inflammatory Drugs Containing an N-Acyl Hydrazone Subunit
(Mdpi Ag, 2014-04-01)
A series of anti-inflammatory derivatives containing an N-acyl hydrazone subunit (4a-e) were synthesized and characterized. Docking studies were performed that suggest that compounds 4a-e bind to cyclooxygenase (COX)-1 and ...
Vanadium complexes with hydrazone or thiosemicarbazone ligands as potential anti-mycobacterium tuberculosis agents
(Bentham Science Publishers, 2015)
Tuberculosis (TB) is an infectious disease caused mainly by Mycobacterium tuberculosis (MTB) and still an important public health problem worldwide. Some factors like the emergence of multidrug resistant (MDR) and extensively ...
Thiosemicarbazones, semicarbazones, dithiocarbazates and hydrazide/hydrazones: Anti-Mycobacterium tuberculosis activity and cytotoxicity
(Elsevier France-editions Scientifiques Medicales Elsevier, 2010-05-01)
The aim of this study was to identify a candidate drug for the development of anti-tuberculosis therapy from previously synthesized compounds based on the thiosemicarbazones, semicarbazones, dithio-carbazates and ...
Thiosemicarbazones, semicarbazones, dithiocarbazates and hydrazide/hydrazones: Anti-Mycobacterium tuberculosis activity and cytotoxicity
(Elsevier France-editions Scientifiques Medicales Elsevier, 2010-05-01)
The aim of this study was to identify a candidate drug for the development of anti-tuberculosis therapy from previously synthesized compounds based on the thiosemicarbazones, semicarbazones, dithio-carbazates and ...
Antiaging activity, molecular docking, and prediction of percutaneous absorption parameters of quinoline?hydrazone hybrids
(Medicinal Chemistry Research, 2020)
Antiplatelet and Antithrombotic Activities of Non-Steroidal Anti-Inflammatory Drugs Containing an N-Acyl Hydrazone Subunit
(Mdpi Ag, 2014-02-01)
Nonsteroidal anti-inflammatory drugs (NSAIDs) 1-5 containing an N-acyl hydrazone subunit were prepared and their antiplatelet and antithrombotic activities assessed in vitro and in vivo. Compounds 1-5 inhibited the platelet ...
Electrochemical studies of grid and linear type M2+ (M=Zn, Cd and Pb) complexes of a bis-(hydrazone) bearing two symmetric carboxylic groups.
(2018-07-24)
Herein we present the preparation of a bis-(hydrazone) containing a pyridine-pyrimidinepyridine
framework. This compound can be visualized as a double arm system able of coordinating
two metal ions in a terpyridine-like ...