Introduction: The human pineal gland exhibits endocrine activity derived from the diencephalon and is divided into lobules by pial connective tissue. Its morphometry and cellularity might be set up during the early years ...

Following the discovery of the melatonin by Lerner et al. (1958), new research and perspectives were developed in order to improve the knowledge regarding the pineal gland. This hormone is not only related to the circadian ...

Antidepressants increase melatonin levels, but it is still unclear whether this effect is related to the improvement of depressive symptoms or to unrelated pharmacological action of antidepressants. To answer this question, ...

Abstract: The recent advances of the psychoneuroimmunology have demonstrated the existence of a physiological anti-inflammatory antitumor neuroendocrine axis, mainly constituted by the pineal gland through its indole hormone ...

The website and database https://snengs.nichd.nih.gov provides RNA sequencing data from multi-species analysis of the pineal glands from zebrafish (Danio rerio), chicken (White Leghorn), rat (Rattus novegicus), mouse (Mus ...

Após a descoberta da melatonina por Lerner et al. (1958), novas pesquisas e perspectivas surgiram tornando a pineal uma estrutura mais estudada. Além disso, sabe-se que este hormônio está relacionado com o controle circadiano ...

Melatonin is secreted by the pineal gland and this is linked to the day/night cycle. It is an antioxidant and plays a fundamental role in the regulation of the jet-lag stage, in several physiological reactions and in control ...