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Characterization and functions of beta defensins in the epididymis
(Medknow Publications & Media Pvt Ltd, 2007-07-01)
The epididymal beta-defensins have evolved by repeated gene duplication and divergence to encode a family of proteins that provide direct protection against pathogens and also support the male reproductive tract in its ...
Green tea extract and its major constituent, epigallocatechin-3-gallate, induce epithelial beta-defensin secretion and prevent beta-defensin degradation by Porphyromonas gingivalis
(Wiley-Blackwell, 2014-10-01)
Background and Objective: Antimicrobial peptides, such as beta-defensins, secreted by gingival epithelial cells, are thought to play a major role in preventing periodontal diseases. In the present study, we investigated ...
Cervicovaginal Levels of Human Beta-Defensin 1, 2, 3 and 4 of Reproductive-Aged Women with Chlamydia trachomatis Infection.
(Sage Publications Inc, 2017-03-01)
Novel androgen-induced activity of an antimicrobial beta-defensin: Regulation of Wolffian duct morphogenesis
(Elsevier Ireland Ltd, 2017)
The Wolffian duct (WD) undergoes morphological changes induced by androgens to form the epididymis, which is an organ essential for sperm maturation. Androgen action in WD epithelium involves paracrine factors of mesenchymal ...
Vaginal human beta defensin 3 deficiency in the presence of bacterial community with no lactobacilli-dominated flora
(Sage Publications Inc, 2015-03-01)
Human beta defensin-4 and keratinocyte growth factor gene expression in cultured keratinocyte and fibroblasts of burned patients
(Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia, 2014-01-01)
PURPOSE: To evaluate KGF and human beta defensin-4 (HBD-4) levels produced by dermic fibroblasts and keratinocytes cultivated from burned patients' skin samples.METHODS: Keratinocytes and fibroblasts of 10 patients (four ...
Human beta-defensin 2 and protease activated receptor-2 expression in patients with chronic periodontitis
(PERGAMON-ELSEVIER SCIENCE LTDOXFORD, 2012)
Objective: Some previous studies have shown that gingipains, trypsin-like proteases produced by Porphyromonas gingivalis, up-regulate human beta defensin-2 (HBD-2) mRNA expression through protease-activated receptor-2 ...