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Cell Volume Regulation in Cultured Human Retinal Müller Cells Is Associated with Changes in Transmembrane Potential
(Public Library of Science, 2013-02)
Müller cells are mainly involved in controlling extracellular homeostasis in the retina, where intense neural activity alters ion concentrations and osmotic gradients, thus favoring cell swelling. This increase in cell ...
Release of taurine and glutamate contributes to cell volume regulation in human retinal Müller cells: Differences in modulation by calcium
(American Physiological Society, 2018-09)
Neuronal activity in the retina generates osmotic gradients that lead to Müller cell swelling, followed by a regulatory volume decrease (RVD) response, partially due to the isoosmotic efflux of KCl and water. However, our ...
Cell Volume Regulation in Human Retinal Müller Cells is Associated with Changes in Transmembrane Potential
(Public Library of Science, 2013-02-25)
Müller cells are mainly involved in controlling extracellular homeostasis in the retina, where intense neural activity alters ion concentrations and osmotic gradients, thus favoring cell swelling. This increase in cell ...
TRPV4 Contributes to Resting Membrane Potential in Retinal Müller Cells: Implications in Cell Volume Regulation
(Wiley-liss, Div John Wiley & Sons Inc, 2017-08)
Neural activity alters osmotic gradients favoring cell swelling in retinal Müller cells. This swelling is followed by a regulatory volume decrease (RVD), partially mediated by an efflux of KCl and water. The transient ...
Viability of primary human pigment epithelium cells and muller-glia cells after intravitreal ziv-aflibercept and aflibercept
(Taylor & Francis Inc, 2016)
Purpose: The aim of this study was to access the safety profiles of 2 fusion proteins with anti-vascular endothelial growth factor action (ziv-aflibercept and aflibercept) on retinal pigment epithelium cells and Muller-Glia ...
Insulin-induced exocytosis regulates the cell surface level of low-density lipoprotein-related protein-1 in müller glial cells
(Portland Press, 2018-05)
Low-density lipoprotein (LDL) receptor-related protein-1 (LRP1) is expressed in retinal Müller glial cells (MGCs) and regulates intracellular translocation to the plasma membrane (PM) of the membrane proteins involved in ...
Activated α2-macroglobulin induces Müller glial cell migration by regulating MT1-MMP activity through LRP1
(Federation of American Societies for Experimental Biology, 2013-05)
In retinal proliferative diseases, Müller glial cells (MGCs) acquire migratory abilities. However, the mechanisms that regulate this migration remain poorly understood. In addition, proliferative disorders associated with ...
Selective Vulnerability of Cancer Cells by Inhibition of Ca2+ Transfer from Endoplasmic Reticulum to Mitochondria
(Elsevier B.V., 2016)
© 2016 The Authors.In the absence of low-level ER-to-mitochondrial Ca2+ transfer, ATP levels fall, and AMPK-dependent, mTOR-independent autophagy is induced as an essential survival mechanism in many cell types. Here, we ...