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Induction of CD4+CD25+FOXP3+ Regulatory T Cells during Human Hookworm Infection Modulates Antigen-Mediated Lymphocyte Proliferation.

Ricci, Natasha Delaqua; Fiuza, Jacqueline Araujo; Bueno, Lilian Lacerda; Cançado, Guilherme Grossi Lopes; Guimaraes, Pedro Henrique Gazzinelli; Martins, Virgillio Gandra; Matoso, Leonardo Ferreira; Miranda, Rodrigo Rodrigues Cambraia de; Geiger, Stefan Michael; Oliveira, Rodrigo Corrêa; Gazzinelli, Andréa Pereira; Fujiwara, Ricardo Toshio; Bartholomeu, Daniella Castanheira (Public Library of Science, 2014)

Excretory-Secretory Products from Hookworm L3 and Adult Worms Suppress Proinflammatory Cytokines in Infected Individuals

Geiger, Stefan Michael; Fujiwara, Ricardo Toshio; Freitas, Paula Albuquerque; Massara, Cristiano Lara; Carvalho, Omar dos Santos; Oliveira, Rodrigo Corrêa; Bethony, Jeffrey Michael (Adenine Press, 2014)

Molecular mechanisms of hookworm disease: Stealth, virulence, and vaccines

Pearson, Mark S.; Tribolet, Leon; Cantacessi, Cinzia; Periago, Maria Victoria; Valerio, Maria Adela; Jariwala, Amar R.; Hotez, Peter J.; Diemert, David J.; Loukas, Alex; Bethony, Jeffrey Michael (Elsevier, 2014)

Cell apoptosis induced by hookworm antigens: a strategy of immunomodulation

Guimarães, Pedro Henrique Gazzinelli; Fagundes, Elaine Maria de Souza; Cançado, Guilherme Grossi Lopes; Martins, Virgillio Gandra; Lemos, Lucas de Carvalho Dhom; Ricci, Natasha Delaqua; Fiuza, Jacqueline Araujo; Bueno, Lilian Lacerda; Miranda, Rodrigo Rodrigues Cambraia de; Guatimosim, Silvia; Oliveira, Andréa Gazzinelli Corrêa de; Oliveira, Rodrigo Corrêa de; Bartholomeu, Daniella Castanheira; Fujiwara, Ricardo Toshio (Frontiers in bioscience, 2018)

Atividade citotóxica e pró-apoptótica de antígenos de ancylostoma ceylanicum: Implicações na modulação da resposta imune na ancilostomíase

Pedro Henrique Gazzinelli Guimaraes (Universidade Federal de Minas GeraisUFMG, 2010-10-29)

Hookworm infection is one of the most prevalent parasitic diseases, infecting an estimated 740 million people in tropical and subtropical regions of the world. A robust but ineffective immune response, characterized by the ...

The human hookworm vaccine

Hotez, Peter J.; Diemert, David; Baconf, Kristina M.; Beaumier, Coreen; Bethony, Jeffrey M.; Bottazzi, Maria Elena; Brooker, Simon; Couto, Artur Roberto; Freire, Marcos da Silva; Homma, Akira; Leef, Bruce Y.; Loukas, Alex; Loblacka, Marva; Morel, Carlos Medicis; Oliveira, Rodrigo Correa; Russell, Philip K. (Elsevier, 2016)

The Human Hookworm Vaccine

Hotez, Peter Jay; Diemert, David; Bacon, Kristina M.; Beaumier, Coreen; Bethony, Jeffrey Michael; Bottazzi, Maria Elena; Brooker, Simon; Couto, Artur Roberto; Freire, Marcos da Silva; Homma, Akira; Lee, Bruce Y.; Loukas, Alex; Loblack, Marva; Morel, Carlos Medicis; Oliveira, Rodrigo Corrêa de; Russell, Philip K. (Elsevier Science, 2018)

Necator americanus and Helminth Co-Infections: Further Down-Modulation of Hookworm-Specific Type 1 Immune Responses

Geiger, Stefan Michael; Alexander, Neal Douglas Edward; Fujiwara, Ricardo Toshio; Brooker, Simon; Cundill, Bonnie; Diemert, David Joseph; Oliveira, Rodrigo Corrêa; Bethony, Jeffrey Michael (Public Library of Science, 2014)

Safety and immunogenicity of the Na-GST-1 hookworm vaccine in Brazilian and American adults

Diemert, David J.; Freire, Janaína; Vanderson, Valente; Talles, Federico; Grahek, Shannon; Campbell, Doreen; Jariwala, Amar; Periago, Maria Victoria; Enk, Martin; Gazzinelli, María Flavia; Bottazzi, María Elena; Hamilton, Roberto; Brelsford, Jill; Yakovleva, Anna; Guangzhao, Li; Peng, Jin; Correa Oliveira, Rodrigo; Hotez, Peter; Bethony, Jeffrey (Public Library Of Science, 2017-05-02)

Necator americanus Glutathione-S-Transferase-1 (Na-GST-1) plays a role in the digestion of host hemoglobin by adult N. americanus hookworms. Vaccination of laboratory animals with recombinant Na-GST-1 is associated with ...

Generalized urticaria induced by the Na-ASP-2 hookworm vaccine: implications for the development of vaccines against helminths

Diemert, David J.; Pinto, Antonio G.; Moura, Janaina Freire de; Jariwala, Amar; Santiago, Helton da Costa; Hamilton, Robert G.; Periago, Maria Victoria; Loukas, Alex; Tribolet, Leon; Mulvenna, Jason; Oliveira, Rodrigo Correa de; Hotez, Peter J.; Bethony, Jeffrey Michael (American Academy of Allergy, 2015)