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Recent Insights on the Medicinal Chemistry of Sickle Cell Disease
(Bentham Science Publ Ltd, 2011-05-01)
Sickle Cell Disease (SCD) is one of the most prevalent hematological diseases in the world. SCD is a genetic disease characterized by punctual mutation that basis on the exchange of glutamic acid to valine in a beta chain ...
Recent Insights on the Medicinal Chemistry of Sickle Cell Disease
(Bentham Science Publ Ltd, 2011-05-01)
Sickle Cell Disease (SCD) is one of the most prevalent hematological diseases in the world. SCD is a genetic disease characterized by punctual mutation that basis on the exchange of glutamic acid to valine in a beta chain ...
Recent Insights on the Medicinal Chemistry of Sickle Cell Disease
(Bentham Science Publ Ltd, 2014)
Spin Label Studies of the Hemoglobin–Membrane Interaction During Sickle Hemoglobin Polymerization
(Springer Wien, 2010-05)
An enhanced hemoglobin–membrane association has been previously documented in sickle cell anemia. However, it is not known how this interaction is modified during the hemoglobin S polymerization process. In this work, we ...
AHSP and beta-thalassemia: A possible genetic modifier
(Taylor & Francis LtdAbingdonInglaterra, 2005)
Vasoactive properties of synthetic blood substitutes
(Medicina (buenos Aires), 1998-01-01)
There is a great need for the development of a safe and efficient blood substitute, to overcome the important limitations of homologous blood transfusion. Currently available cell-free hemoglobin-based oxygen-carrying ...
Avaliação da albumina modificada pela isquemia na anemia associada à doença renal crônica
(Universidade Federal de Santa MariaBRAnálises Clínicas e ToxicológicasUFSMPrograma de Pós-Graduação em Ciências Farmacêuticas, 2007-12-19)
Chronic kidney disease (CKD) is highly prevalent, with increasing numbers of patients affected by the disease world-wide, and anemia is a common finding in patients with CKD. Anemia impacts negatively on cardiovascular ...
Characterization and oxygen binding properties of des-Arg human hemoglobin
(Associação Brasileira de Divulgação Científica (ABRADIC), 2009-06-01)
The role of chloride in the stabilization of the deoxy conformation of hemoglobin (Hb), the low oxygen affinity state, has been studied in order to identify the nature of this binding. Previous studies have shown that ...
Characterization and oxygen binding properties of des-Arg human hemoglobin
(Associação Brasileira de Divulgação Científica (ABRADIC), 2009-06-01)
The role of chloride in the stabilization of the deoxy conformation of hemoglobin (Hb), the low oxygen affinity state, has been studied in order to identify the nature of this binding. Previous studies have shown that ...