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P2X7R large pore is partially blocked by pore forming proteins antagonists in astrocytes
(Springer Verlag, 2016)
Atp and glutamate released via astroglial connexin 43 hemichannels mediate neuronal death through activation of pannexin 1 hemichannels
(WILEY-BLACKWELL, 2011)
Inflammation contributes to neurodegeneration in post-ischemic brain, diabetes, and Alzheimer's disease. Participants in this inflammatory response include activation of microglia and astrocytes. We studied the role of ...
GABAergic Regulation of Astroglial Gliotransmission through Cx43 Hemichannels
(2022)
Gamma-Aminobutyric acid (GABA) is the primary inhibitory neurotransmitter in the brain. It is produced by interneurons and recycled by astrocytes. In neurons, GABA activates the influx of Cl- via the GABAA receptor or ...
GABAergic Regulation of Astroglial Gliotransmission through Cx43 Hemichannels
(MDPI, 2022-11)
Gamma-Aminobutyric acid (GABA) is the primary inhibitory neurotransmitter in the brain. It is produced by interneurons and recycled by astrocytes. In neurons, GABA activates the influx of Cl- via the GABAA receptor or ...
Is pannexin the pore associated with the P2X7 receptor?
(Springer-Verlag Berlin Heidelberg, 2015)
Astroglial Ca2+-Dependent Hyperexcitability Requires P2Y1 Purinergic Receptors and Pannexin-1 Channel Activation in a Chronic Model of Epilepsy
(2018)
Astrocytes from the hippocampus of chronic epileptic rats exhibit an abnormal pattern of intracellular calcium oscillations, characterized by an augmented frequency of long lasting spontaneous Ca2C transients, which are ...
Regulation of ventral surface CO2/H+-sensitive neurons by purinergic signalling
(WILEY-BLACKWELLMALDEN, 2012)
Central chemoreception is the mechanism by which the brain regulates breathing in response to changes in tissue CO2/H+. Abrainstemregion called the retrotrapezoid nucleus (RTN) contains a population of CO2/H+-sensitive ...
Ca2+ signaling in injured in situ endothelium of rat aorta
(Elsevier, 2008-09)
The inner wall of excised rat aorta was scraped by a microelectrode and Ca2+ signals were investigated by fluorescence microscopy in endothelial cells (ECs) directly coupled with injured cells. The injury caused an immediate ...
Papel de hemicanales en el daño auditivo inducido por ruido mediada por la activación de receptor de adenosina A2A
(2020)
Noise-induced hearing loss is one of the leading causes of acquired hearing loss. In it, different structural and functional alterations occur in the cochlea. Various studies have released adenosine as an otoprotector ...