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Desenvolvimento farmacotécnico e validação analítica de comprimidos revestidos gastrorresistentes a partir do extrato padronizado de Harpagophytum procumbens DC
(Universidade Federal de São Paulo, 2017-03-24)
The project aimed to develop a traditional herbal medicine from the dry extract,
standardized in harpagoside, from the secondary roots of the plant species
Harpagophytum procumbens DC. (Pedaliaceae), popularly known as ...
Avaliação do efeito do extrato etanólico bruto de Harpagophytum procumbens em camundongos infectados com Toxocara canis
(Universidade Federal de São CarlosBRUFSCarPrograma de Pós-Graduação em Biotecnologia - PPGBiotec, 2012-02-29)
The Syndrome of Visceral Larva Migrans (VLMS) is a parasitic disease caused by Toxocara canis, one of the most common helminthes in dogs. In the definitive hosts are present in different morphological forms, embryonated ...
Ação do tratamento com Mentha piperita L. e Harpagophytum procumbens contra Schistosoma mansoni - in vitro: análise proteômica
(Universidade Federal de São CarlosBRUFSCarPrograma de Pós-Graduação em Biotecnologia - PPGBiotec, 2014-08-08)
Mansonic schistosomiasis is a disease that infected more than 240 million people worldwide, it is caused by Schistosoma mansoni. It is the second only to malaria in public health importance. The only drug currently effective ...
Efeito anti-inflamatório do extrato etanólico da Harpagophytum procumbens durante a inflamação intestinal de camundongos infectados com Salmonella Enteritidis (ATCC13076)
(Universidade Federal de São CarlosBRUFSCarPrograma de Pós-Graduação em Biotecnologia - PPGBiotec, 2014-05-29)
Salmonellosis is an illness caused by bacteria of the genus Salmonella, a leading infectious disease worldwide. Due to the importance of this infection forward to eating habits, the search for a new compound that can ...
Effect of Isolated Fractions of Harpagophytum procumbens DC (Devil`s Claw) on COX-1, COX-2 Activity and Nitric Oxide Production on Whole-Blood Assay
(WILEY-BLACKWELL, 2010)
The present study evaluates the effect of isolated fractions of Harpagophytum procumbens (devil`s claw) on cyclooxygenase (COX-1 and COX-2) activities and NO production using a whole blood assay. The activity of COX-1 was ...
Efeito do Harpagophytum procumbens sobre parâmetros de estresse oxidativo e a viabilidade celular in vitro
(Universidade Federal de Santa MariaBRFarmacologiaUFSMPrograma de Pós-Graduação em Farmacologia, 2013-10-04)
Harpagophytum procumbens, known as devil's claw, is an African plant with numerous therapeutic effects, among which stands out for its powerful anti-inflammatory action, but the mechanism by which exerts its effect is not ...
Determination of harpagoside in Harpagophytum procumbens DC tablet’s using analytical method by High Performance Liquid Chromatography
(Instituto de Química da Universidade do Estado de São Paulo - UNESP, 2020)
Influência de Harpagophytum procumbens sobre parâmetros comportamentais e moleculares em um modelo de discinesia orofacial em ratos
(Universidade Federal de Santa MariaBrasilFarmacologiaUFSMPrograma de Pós-Graduação em FarmacologiaCentro de Ciências da Saúde, 2017-02-18)
Fluphenazine is a typical antipsychotic used for the treatment of schizophrenia. However, its chronic use has been related to the appearance of extrapyramidal side effects, such as tardive dyskinesia (TD). Studies suggest ...
Risk Assessment via Metabolism and Cell Growth Inhibition in a HepG2/C3A Cell Line Upon Treatment with Arpadol and its Active Component Harpagoside
(Wiley-Blackwell, 2017-03-01)
Harpagophytum procumbens (Hp) has been used as antiinflammatory and analgesic agent for the treatment of rheumatic diseases. The principal active component of Hp is harpagoside (HA). We tested the toxicity of this new ...
Pesquisa e Desenvolvimento de Fitoterápicos: Relatos de Experiência em Indústria Farmacêutica Nacional
(Fundação Oswaldo Cruz. Farmanguinhos. Núcleo de Gestão em Biodiversidade e Saúde., 2017)