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The effect of harmaline on force of contraction of the rat isolated atrium

Chamorro, Hernan; Narvarte, Javier; Diaz, Gabriela; Carpentier, Robert (1975)

In rat isolated right atria, beating spontaneously at 30°C, harmaline 8.3 × 10-5 M slowed atrial rate and enhanced force of contraction. The velocity of development of tension (dT/dt) increased and time to peak tension was ...

Effect of harmaline on pacemaker activity of guinea pig sinus node

Carpentier, Robert; Narvarte, Javier; Sanhueza, Sylvia (1977)

Transmembrane potentials of pacemaker fibers of the sinus node were recorded to analyze the effect of harmaline (HME) on cardiac automaticity. A short exposure to HME 2.1 × 10-5 or 8.3 × 10-5 M produced a long lasting ...

Dual inotropic effect of harmaline on the rat heart atrial muscle

Carpenter, Robert; Diaz, Gabriela (1977)

The effect of harmaline (HME) was analyzed in rat strips superfused in vitro. A dual inotropic action was found: the positive component was due to a transient catechol-mediated enhancement of the velocity of development ...

Cytotoxicity of the β- carboline alkaloids harmine and harmaline in human cell assays in vitro01.

JUDITH JIMENEZ GUZMAN; LETICIA RIVERON NEGRETE; FIKRAT ABDULLAEV JAFAROVA; JESUS JAVIER ESPINOSA AGUIRRE; ROSARIO RODRIGUEZ ARNAIZ (Elsevier, 2008)

Effects of unilateral stereotactic posterior striatotomy on harmaline-induced tremor in rats

Vilela Filho, Osvaldo [UNIFESP]; Ferraz, Fernando P. [UNIFESP]; Barros, Breno A.; Silva, Luciana O.; Anunciacao, Suzana F.; Souza, Joaquim T.; Silva, Delson J.; Leite, Mauricio B.; Atayde, Ingrid B.; Ragazzo, Paulo C.; Barreto, Paula G.; Nobrega, Mariana A.; Araujo, Maisa R.; Santos, Mayra R.; Ala, Victor H.; Queiroz, Stefano T. (Wiley-Blackwell, 2013-10-01)

Although long known and the most prevalent movement disorder, pathophysiology of essential tremor (ET) remains controversial. the most accepted hypothesis is that it is caused by a dysfunction of the olivocerebellar system. ...

Catechol-mediated effects of harmaline on the action potential of rat atrial fibres

Carpentier,; Narvarte,; Sanhueza, (Oxford University Press, 1977)

Summary: The mechanism of the transient enhancement of the amplitude of the action potential (AAP) induced by harmaline (HME) was studied in rat atria. The results show that HME increases AAP through an enhancement of the ...

Catechol mediated effects of harmaline on the action potential of rat atrial fibres

Carpentier,; Narvarte,; Sanhueza, Luis (1977)

The mechanism of the transient enhancement of the amplitude of the action potential (AAP) induced by harmaline (HME) was studied in rat atria. The results show that HME increases AAP through an enhancement of the slow ...

Effects of some β-carboline alkaloids on intact Trypanosoma cruzi epimastigotes

Rivas, Pilar; Cassels Niven, Bruce; Morello Casté, Antonio; Repetto Scaramelli, Yolanda (1999)

Several β-carboline (9H-pyrido-[3,4-b]-indole) alkaloids were evaluated for in vitro trypanosomicidal activity against Trypanosoma cruzi epimastigotes belonging to two different strains (Tulahuen and LQ) showing different ...

Positive inotropic effect of harmaline on the isolated rat atrium EFECTO INOTROPO POSITIVO DE LA HARMALINA EN LA AURICULA AISLADA DE RATA

Diaz, Eloisa; Narvarte,; Chamorro, G.; Carpentier, (1976)

Light-induced full aromatization and hydroxylation of 7-methoxy-1-methyl-3,4-dihydro-2H-pyrido[3,4-b]indole alkaloid : Oxygen partial pressure as a key modulator of the photoproducts distribution

Villarruel, Fernando D.; Denofrio, María Paula; Rasse Suriani, Federico Ariel Osvaldo; García Einschlag, Fernando Sebastián; Schmidt de León, Tobías; Erra-Balsells, Rosa; Cabrerizo, Franco Martín (2019)