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Influence of hairy root ecotypes on production of tropane alkaloids in Brugmansia candida
(Springer, 2013-09)
Hyoscyamine and scopolamine are tropane alkaloids widely applied in medicine. Differences in alkaloids production and growth kinetics were observed for Argentinean and Colombian ecotypes of Brugmansia candida hairy roots. ...
Production of tropane alkaloids by biotransformation using recombinant Escherichia coli whole cells
(Elsevier Science Sa, 2017-09)
Tropane alkaloids, such as hyoscyamine, 6β-hydroxyhyoscyamine and scopolamine, are secondary metabolites that were traditionally applied in medicine due to their anticholinergic activity. Hyoscyamine is converted into ...
Analytical considerations for the successful evaluation of hyoscyamine biotransformation into 6b-hydroxyhyoscyamine and scopolamine
(Colegio de Farmacéuticos de la Provincia de Buenos Aires, 2012-05)
Hyoscyamine, 6B-hydroxyhyoscyamine and scopolamine are anticholinergic agents that be-long to the tropane alkaloids, a pharmacological important group of secondary metabolites. Hyoscyamine and scopolamine were historically ...
Analysis and sequencing of h6hmRNA, last enzyme in the tropane alkaloids pathway from anthers and hairy root cultures of Brugmansia candida (Solanaceae)
(Pontificia Universidad Católica de Valparaíso, 2006)