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The Hus1 homologue of Leishmania major encodes a nuclear protein that participates in DNA damage response
(ELSEVIER SCIENCE BV, 2011)
The protozoan parasite Leishmania presents a dynamic and plastic genome in which gene amplification and chromosome translocations are common phenomena. Such plasticity hints at the necessity of dependable genome maintenance ...
Jan Hus: as cartas de um educador e seu legado imortal
(Universidade de São Paulo, 2010)
Esta tese é um estudo da figura de Jan Hus, tradicionalmente conhecido como reformador religioso da Boêmia do século XV, olhando-o sob a perspectiva da História da Educação. Inspirados nas propostas metodológicas de Carlo ...
Association of haemolytic uraemic syndrome with dysregulation of chemokine receptor expression in circulating monocytes
(Portland Press, 2015-08)
Haemolytic uraemic syndrome (HUS) is the major complication of Escherichia coli gastrointestinal infections that are Shiga toxin (Stx) producing. Monocytes contribute to HUS evolution by producing cytokines that sensitize ...
Severely ill pediatric patients with Shiga toxin-associated hemolytic uremic syndrome (STEC-HUS) who suffered from multiple organ involvement in the early stage
(Springer, 2020-11)
Background: Shiga toxin-producing Escherichia coli-associated hemolytic uremic syndrome (STEC-HUS) is the main cause of pediatric acute kidney injury (AKI) in Argentina. Endothelial injury is the trigger event in the ...
Hemolytic uremic syndrome: pathogenesis and update of interventions
(Future Drugs Ltd., 2009-12)
The typical form of hemolytic uremic syndrome (HUS) is the major complication of Shiga toxin-producing Escherichia coli infections. HUS is a critical health problem in Argentina since it is the main cause of acute renal ...
Pathogenic role of inflammatory response during Shiga toxin-associated hemolytic uremic syndrome (HUS)
(Springer, 2018-11)
Hemolytic uremic syndrome (HUS) is defined as a triad of noninmune microangiopathic hemolytic anemia, thrombocytopenia, and acute kidney injury. The most frequent presentation is secondary to Shiga toxin (Stx)-producing ...
Caracterização funcional do gene Hus1 de Trypanosoma cruzi
(Universidade Federal de Minas GeraisBrasilICB - INSTITUTO DE CIÊNCIAS BIOLOGICASPrograma de Pós-Graduação em Bioquímica e ImunologiaUFMG, 2015-02-20)
The DNA damage response (DDR) is a coordinated mechanism of damage signaling, in which lesion detection leads to cell cycle arrest and recruitment of repair machinery. One branch of the DDR is activated by the ATR kinase. ...
Development of camelid single chain antibodies against Shiga toxin type 2 (Stx2) with therapeutic potential against Hemolytic Uremic Syndrome (HUS).
(Nature publishing group, 2016-04)
Shiga toxin (Stx)-producing Escherichia coli (STEC) infections are implicated in the development of the life-threatening Hemolytic Uremic Syndrome (HUS). Despite the magnitude of the social and economic problems caused by ...
Role of polymorphonuclear leukocytes in the pathophysiology of typical hemolytic uremic syndrome
(HINDAWI publishing Corporation, 2007-08)
Thrombotic microangiopathy and acute renal failure are cardinal features of post-diarrheal hemolytic uremic syndrome (HUS). These conditions are related to endothelial and epithelial cell damage induced by Shiga toxin ...
Jan Hus: as cartas de um educador e seu legado imortal
(Universidade de São Paulo, 2010)
Esta tese é um estudo da figura de Jan Hus, tradicionalmente conhecido como reformador religioso da Boêmia do século XV, olhando-o sob a perspectiva da História da Educação. Inspirados nas propostas metodológicas de Carlo ...