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Produtos Naturais Inibidores da Transcriptase Reversa do Vírus HIVNatural Products as HIV Reverse Transcriptase Inhibitors
(Fundação Oswaldo Cruz. Farmanguinhos. Núcleo de Gestão em Biodiversidade e Saúde., 2017)
Structure-based evaluation of C5 derivatives in the catechol diether series targeting HIV-1 reverse transcriptase
(Wiley, 2014-05)
Using a computationally driven approach, a class of inhibitors with picomolar potency known as the catechol diethers were developed targeting the non-nucleoside-binding pocket of HIV-1 reverse transcriptase. Computational ...
Design, synthesis and biological evaluation of quinoxaline compounds as anti-HIV agents targeting reverse transcriptase enzyme
(Elsevier France-Editions Scientifiques Medicales Elsevier, 2020-02)
Infection by human immunodeficiency virus still represents a continuous serious concern and a global threat to human health. Due to appearance of multi-resistant virus strains and the serious adverse side effects of the ...
Coexistencia de variantes HIV-1 com insercao dipeptidica no gene da transcriptase reversaCoexistencia de variantes de VIH-1 con insercion dipeptidica en el gen de la transcriptasa inversaCoexistence of HIV-1 variants with dipeptidic insertion in the reverse transcriptase gene
(Universidade de São Paulo (USP), Faculdade de Saúde Pública, 2014)
2´,3´-Dialdehyde of ATP, ADP, and Adenosine Inhibit HIV-1 Reverse Transcriptase and HIV-1 Replication
(Bentham Science Publishers, 2017)
Potent inhibitors active against HIV reverse transcriptase with K101P, a mutation conferring rilpivirine resistance
(American Chemical Society, 2015-09)
Catechol diether compounds have nanomolar antiviral and enzymatic activity against HIV with reverse transcriptase (RT) variants containing K101P, a mutation that confers high-level resistance to FDA-approved non-nucleoside ...