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HGPRT: enzima recombinante de Schistosoma mansoni e sua ação na imunoterapia durante a esquistossomose murina
(Universidade Federal de São CarlosUFSCarCâmpus São CarlosCiências Biológicas - CB, 2016-06)
Schistosomiasis is a chronic parasitic disease and neglected, caused by the flatworm Schistosoma sp and affects 240 million people around the world. In Brazil is considered expanding and reaches 19 states. Schistosoma ...
Efeitos da imunização com Adenosina Quinase (AK) e Hipoxantina-Guanina Fosforibosiltransferase (HGPRT) recombinantes de Schistosoma mansoni : controle da infecção murina
(Universidade Federal de São CarlosUFSCarPrograma de Pós-Graduação em Genética Evolutiva e Biologia Molecular - PPGGEvCâmpus São Carlos, 2016-02-24)
The mansoni schistosomiasis is the most important of human helminthiasis. Despite advances in its
control this disease continues to spread to new geographical areas. It currently affects more than 250
million people. ...
Efeito das enzimas recombinantes de Schistosoma mansoni Hipoxantina-Guanina Fosforibosiltransferase (HGPRT) e Purina Nucleosídeo Fosforilase (PNP) no tratamento da esquistossomose experimental
(Universidade Federal de São CarlosUFSCarPrograma de Pós-Graduação em Genética Evolutiva e Biologia Molecular - PPGGEvCâmpus São Carlos, 2018-02-26)
Schistosomiasis is a disease that affects a large number of people in 78 countries. The
number of cases has increased in recent years and there is no vaccine and new drugs, a
worrying aspect, since there is loss of ...
Lesch-Nyhan disease in two families from Chiloe island with mutations in the HPRT1 gene
(Taylor & Francis, 2017)
Lesch-Nyhan disease (LND) is a rare X-linked inherited neurogenetic disorder of purine metabolism in which the enzyme, hypoxanthine-guanine phosphoribosyltransferase (HGprt) is defective. The authors report two independent ...
Cytotoxicity, genotoxicity and antimutagenicity of hexane extracts of Agaricus blazei determined in vitro by the comet assay and CHO/HGPRT gene mutation assay
(Elsevier B.V., 2005-06-01)
Agaricus blazei Murrill ss. Heinem, known as the sun mushroom or himematsutake, is a basidiomycete native to Brazil, which is popular for its medicinal properties. The aim of this study was to test hexane extracts (one ...
Cytotoxicity, genotoxicity and antimutagenicity of hexane extracts of Agaricus blazei determined in vitro by the comet assay and CHO/HGPRT gene mutation assay
(Elsevier B.V., 2005-06-01)
Agaricus blazei Murrill ss. Heinem, known as the sun mushroom or himematsutake, is a basidiomycete native to Brazil, which is popular for its medicinal properties. The aim of this study was to test hexane extracts (one ...
Cytotoxicity and genotoxicity of Agaricus blazei methanolic extract fractions assessed using gene and chromosomal mutation assays
(Sociedade Brasileira de Genética, 2008-01-01)
Functional food investigations have demonstrated the presence of substances that could be beneficial to human health when consumed. However, the toxic effects of some substances contained in foods have been determined. ...
Cytotoxicity and genotoxicity of Agaricus blazei methanolic extract fractions assessed using gene and chromosomal mutation assays
(Sociedade Brasileira de Genética, 2008-01-01)
Functional food investigations have demonstrated the presence of substances that could be beneficial to human health when consumed. However, the toxic effects of some substances contained in foods have been determined. ...
Hypoxanthine-guanine phosphoribosyltransferase from Mycobacterium tuberculosis H37Rv: Cloning, expression, and biochemical characterization
(Academic Press Inc. Elsevier B.V., 2009-08-01)
Human tuberculosis (TB) is a major cause of morbidity and mortality worldwide, especially in poor and developing countries. Moreover, the emergence of Mycobacterium tuberculosis strains resistant to first- and second-line ...