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Structural features and anticoagulant activities of a novel natural low molecular weight heparin from the shrimp Penaeus brasiliensis
(Elsevier B.V., 1999-08-05)
A natural low molecular weight heparin (8.5 kDa), with an anticoagulant activity of 95 IU/mg by the USP assay, was isolated from the shrimp Penaeus brasiliensis. the crustacean heparin was susceptible to both heparinase ...
Uncoupling of actomyosin adenosinetriphosphatase by heparin and its fragments
(Springer, 1997-04-01)
Heparin and its enzymatic fragments, prepared by degradation of heparin with heparinase from Flavo-bacterium heparinum, were capable of inhibiting the actomyosin-ATPase activity obtained from striated and smooth vascular ...
Heparins and heparinoids: Occurrence, structure and mechanism of antithrombotic and hemorrhagic activities
(Bentham Science Publ Ltd, 2004-01-01)
The correlation between structure, anticloting, antithrombotic and hemorrhagic activities of heparin, heparan sulfate, low molecular weight heparins and heparin-like compounds from various sources that are in used in ...
Beneficial non-anticoagulant mechanisms underlying heparin treatment of COVID-19 patients
Coronavirus disease-2019 (COVID-19) is associated with severe inflammation in mainly the lung, and kidney.
Reports suggest a beneficial effect of the use of heparin/low molecular weight heparin (LMWH) on mortality
in ...
The interaction between heparin and Lys49 phospholipase A(2) reveals the natural binding of heparin on the enzyme
(Elsevier B.V., 2005-10-30)
We have studied at a molecular level the interaction of heparins on bothropstoxin-1 (BthTx-1), a phospholipase A(2) toxin. The protein was monitored using gel filtration chromatography, dynamic light scattering (DLS), ...
The interaction between heparin and Lys49 phospholipase A(2) reveals the natural binding of heparin on the enzyme
(Elsevier B.V., 2005-10-30)
We have studied at a molecular level the interaction of heparins on bothropstoxin-1 (BthTx-1), a phospholipase A(2) toxin. The protein was monitored using gel filtration chromatography, dynamic light scattering (DLS), ...
Effect of heparin on in vitro capacitation of boar sperm
(Sociedad de Biología de Chile, 2006)
Heparin receptors in two murine mammary adenocarcinomas with different metastatic ability: relationship with growth inhibition
(Elsevier, 1995-04-14)
Binding of heparin to primary cultured cells of two murine mammary adenocarcinomas with low (M3) and high (MM3) lung, metastatic capacity was determined. Heparin binding was rapid, specific and saturable. MM3 cells grown ...
Heparin is biocompatible and can induce differentiation of human dental pulp cells
(2019-06-01)
Aim: To investigate the biocompatibility, osteogenic bioactivity and mRNA expression of the osteo/odontogenic markers bone morphogenetic protein 2 (BMP-2), osteocalcin (OC) and alkaline phosphatase (ALP), induced by heparin ...