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Hematopoietic Stem Cells but Not Multipotent Progenitors Drive Erythropoiesis during Chronic Erythroid Stress in EPO Transgenic Mice
(Elsevier, 2018)
The hematopoietic stem cell (HSC) compartment consists of a small pool of cells capable of replenishing all blood cells. Although it is established that the hematopoietic system is assembled as a hierarchical organization ...
In vitro inhibition of murine hematopoietic progenitors and stromal cells by vinorelbine
(Springer, 2000-04)
Hematopoietic progenitor colony assays were used to establish the effects of the vinca alkaloid vinorelbine (VRB) on murine bone marrow. The in vitro growth of colony-forming units-granulocyte/macrophage (CFU-GM), burst ...
Hematopoietic stem cell transplantation: clinical use and perspectives
(SOC BIOLGIA CHILE, 2012)
Hematopoietic stem cell transplantation is the accepted therapy of choice for a variety of malignant and non-malignant diseases in children and adults. Initially developed as rescue therapy for a patient with cancer after ...
Role of NFKB2 on the early myeloid differentiation of CD34+ hematopoietic stem/progenitor cells
(ELSEVIER SCI LTD, 2010)
To better understand the early events regulating lineage-specific hematopoietic differentiation, we analyzed the transcriptional profiles of CD34+ human hematopoietic stem and progenitor cells (HSPCs) subjected to ...
Influencia de la señalización por TLR9 en el desarrollo y destino de los progenitores linfoides tempranos
(22/03/2012)
ABSTRACT: Introduction. In mice, Toll-like receptors can be detected in the most primitive stages of hematopoietic cells, and, when they get stimulated, hematopoietic progenitors proliferate and differentiate bypassing ...
Factors affecting hematopoietic progenitor cell mobilization: An analysis of 307 patients
(PERGAMON-ELSEVIER SCIENCE LTD, 2008)
We reviewed the data of 307 patients treated with autologous bone marrow transplantation with the aim to identify factors associated with poor hematopoietic stern cell (HSC) mobilization after administration of cyclophosphamide ...