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Predictors of Hepatitis C Treatment Failure After Using Direct-Acting Antivirals in People Living With Human Immunodeficiency Virus
Background. Little is known about the influence of ongoing barriers to care in the persistence of hepatitis C virus (HCV) viremia after treatment with direct-acting antivirals (DAAs) among people living with human ...
Hepatitis C virus resistance to the new direct-acting antivirals
(Informa Healthcare, 2016-07)
Introduction: The treatment of hepatitis C virus (HCV) infection has dramatically improved in recent years with the widespread use of interferon-free combination regimens. Despite the high sustained virological response ...
A novel molecular mechanism to explain mutations of the HCV protease associated with resistance against covalently bound inhibitors
(2019-12-01)
NS3 is an important therapeutic target for direct-acting antiviral (DAA) drugs. However, many patients treated with DAAs have unsustained virologic response (UVR) due to the high mutation rate of HCV. The aim of this work ...
Dual role of IL-12 in the therapeutic efficacy or failure during combined PEG-Interferon-α2A and ribavirin therapy in patients with chronic hepatitis C
(Elsevier/North-Holland Biomedical Press, 2018)
Treatment of chronic HCV infection with DAAs in Rio de Janeiro/Brazil: SVR rates and baseline resistance analyses in NS5A and NS5B genes
(Public Library of Science, 2019)
Soroprevalência de hepatite C em pacientes em hemodiálise no Estado de Minas Gerais
(Universidade Federal de Minas GeraisUFMG, 2006-06-29)
Introduction: Hepatitis C is a worldwide public health problem. Patients with chronic renal failure (CRF) in hemodialysis (HD) programs comprise a risk group for acquisition of hepatitis C virus (HCV) infection. HCV ...
Accuracy of serology and molecular diagnosis tests for HBV and HCV in Chronic Renal Failure patients on hemodialysis, Porto Velho, Brazil
(Instituto de Ciências da Saúde/ Universidade Federal da BahiaBrasil, 2009-09)
Abstract:
Patients under hemodialysis treatment for chronic renal failure (CRF) are among the groups with the highest prevalence of
hepatitis B and C viruses due to frequent blood transfusions and nosocomial transmission. ...
Income-driven food insecurity drives treatment non-adherence and virologic failure in HIV/HCV-coinfected individuals
(Universidade Federal de Minas GeraisBrasilFAR - DEPARTAMENTO DE PRODUTOS FARMACÊUTICOSUFMG, 2017-08-22)
Decompensated cirrhosis and liver transplantation negatively impact in DAA treatment response: Real-world experience from HCV-LALREAN cohort
(Wiley-liss, div John Wiley & Sons Inc., 2020-08)
Introduction: Although the effectiveness of direct-acting antivirals (DAAs) for the treatment of chronic hepatitis C virus (HCV) has been reported in real-world settings, predictive factors of treatment failure are lacking. ...
Baseline resistance associated substitutions in HCV genotype 1 infected cohort treated with Simeprevir, Daclatasvir and Sofosbuvir in Brazil
(2019-01-01)
Background: The World Health Organization estimates that 1% of the world population (71 million) is infected with hepatitis C virus (HCV). In 2015, three direct-acting antivirals (DAAs), simeprevir (SMV), sofosbuvir (SOF) ...