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Downregulation of the protein synthesis machinery is a major regulatory event during early adipogenic differentiation of human adipose-derived stromal cells
(Elsevier Science, 2017-12)
Commitment of adult stem cells involves the activation of specific gene networks regulated from transcription to protein synthesis. Here, we used ribosome profiling to identify mRNAs regulated at the translational level, ...
Estratégias de cultivo de células-tronco derivadas do tecido adiposo humano para promover a regeneração tecidual óssea in vivo
(Universidade Federal de Minas GeraisUFMG, 2015-08-17)
Large cranial defects do not regenerate successfully, posing an important biomedical issue. The current approaches to heal the bone tissue still face some limitations and thus, the tissue engineering is an attractive science ...
Producciónn xeno-free de Células Madre Mesenquimales derivadas de tejido adiposo, y evaluación de su secretoma neovasculairzante
(2016)
Introducción. Las moléculas de origen animal o bacteriano que habitualmente son usadas en los protocolos de extracción, cultivo y criopreservación de Células Madre derivadas de Tejido Adiposo humano (human Adipose derived ...
Adipose-derived mesenchymal stem/stromal cells: from the lab bench to the basic concepts for clinical translation
(Instituto de Histología y Embriología "Dr. Mario Burgos", 2018-12)
In the last years, much work has shown that the most effective repair system of the body is represented by stem cells, which are defined as undifferentiated precursors that own unlimited or prolonged self-renewal ability, ...
Downregulation of the protein synthesismachinery is amajor regulatory event during early adipogenic differentiation of human adipose-derived stromal cells
(Elsevier B.V., 2017)
Commitment of adult stemcells involves the activation of specific gene networks regulated fromtranscription to protein synthesis. Here, we used ribosome profiling to identify mRNAs regulated at the translational level, ...
Adipose Tissue-Derived Stem Cells from Humans and Mice Differ in Proliferative Capacity and Genome Stability in Long-Term Cultures
(MARY ANN LIEBERT INC, 2011)
Adipose tissue-derived stem cells (ASCs) are among the more attractive adult stem cell options for potential therapeutic applications. Here, we studied and compared the basic biological characteristics of ASCs isolated ...
Osteogênese de células-tronco humanas em matriz tridimensional de poli-3-hidroxibutirato- co-3-hidroxivalerato utilizando meio suplementado com soro humano
(Universidade Federal de Minas GeraisUFMG, 2011-08-08)
Tissue Engineering is a multidisciplinary science that offers a strategy to circumvent the major problems related with bone regenerative and therapeutic procedures. In its context, the human adipose stem cells (hASC) are ...
Avaliação da diferenciação osteogênica de células-tronco do tecido adiposo humano cultivadas em espuma de vidro bioativo e biorreator de perfusão para engenharia de tecido ósseo
(Universidade Federal de Minas GeraisUFMG, 2012-03-02)
Tissue Engineering is a multidisciplinary science whose goal is to combine a structural matrix and cells to form a construct able to promote regeneration of injured tissue. Bioactive glass foam (BG) produced by sol-gel is ...
Adipose tissue mesenchymal stem cell expansion in animal serum-free medium supplemented with autologous human platelet lysate
(WILEY-BLACKWELL PUBLISHING, INC, 2009)
BACKGROUND: Mesenchymal stem cells (MSCs) have been considered for human regenerative therapy applications, and safe culture and expansion protocols are needed especially in the context of interspecies contamination. Human ...