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Effectiveness of commercial inhibitors against subtype F HIV-1 protease
(TAYLOR & FRANCIS LTD, 2009)
Subtype F wild type HIV protease has been kinetically characterized using six commercial inhibitors (amprenavir, indinavir, lopinavir, nelfinavir, ritonavir and saquinavir) commonly used for HIV/AIDS treatment, as well as ...
Structure-Based Approach for the Study of Estrogen Receptor Binding Affinity and Subtype Selectivity
(AMER CHEMICAL SOC, 2008)
Estrogens exert important physiological effects through the modulation of two human estrogen receptor (hER) subtypes, alpa (hER alpha) and beta (hER beta). Because the levels and relative proportion of hER alpha and hER ...
Inactivation of COX-2, HMLH1 and CDKN2A Gene by Promoter Methylation in Gastric Cancer: Relationship with Histological Subtype, Tumor Location and Helicobacter pylori Genotype
(Karger, 2011-01-01)
Objective: We aimed to evaluate the inactivation of COX-2, HMLH1 and CDKN2A by promoter methylation and its relationship with the infection by different Helicobacter pylori strains in gastric cancer. Methods: DNA extracted ...
Inactivation of COX-2, HMLH1 and CDKN2A Gene by Promoter Methylation in Gastric Cancer: Relationship with Histological Subtype, Tumor Location and Helicobacter pylori Genotype
(Karger, 2011-01-01)
Objective: We aimed to evaluate the inactivation of COX-2, HMLH1 and CDKN2A by promoter methylation and its relationship with the infection by different Helicobacter pylori strains in gastric cancer. Methods: DNA extracted ...
EFFECTS of ENDOTHELIN-3 ON the ISOLATED GUINEA-PIG ILEUM - ROLE of NA+ IONS and ENDOTHELIN RECEPTOR SUBTYPES
(Elsevier B.V., 1992-04-22)
Endothelin-3 induced a relaxation followed by contraction in the isolated guinea-pig ileum. the contractile but not the relaxant component of the response was concentration-dependent in the dose range studied. Neuronal ...
A possible structural determinant of selectivity of boldine and derivatives for the (xlA-adrenoceptor subtype
(Stockton Press, 1996-09-09)
1 The selectivity of action of boldine and the related aporphine alkaloids, predicentrine (9-0-
methylboldine) and glaucine (2,9-0-dimethylboldine) on oel-adrenoceptor subtypes was studied by
examining [3H]-prazosin ...
Invasion of differentiated intestinal Caco-2 cells is a sporadic property among atypical enteropathogenic Escherichia coli strains carrying common intimin subtypes
(2014-01-01)
Atypical enteropathogenic Escherichia coli (aEPEC) strains produce attaching-effacing (AE) lesions on enterocytes due to the interaction of the adhesin intimin with its translocated receptor. aEPEC strain 1551-2 was ...