Now showing items 1-10 of 846
Chaperone mediated autophagy contributes to the newly synthesized histones H3 and H4 quality control
Although there are several pathways to ensure that proteins are folded properly in the cell, little is known about the molecular mechanisms regulating histone folding and proteostasis. In this work, we identified that ...
Evolution of the histones: free play with exon shuffling
(Sociedad de Biología de Chile, 2001)
Extremely divergent histone H4 sequence from trypanosoma cruzi: Evolutionary implications
Trypanosoma cruzi presents six histones electrophoretically resolved in three gel systems. Indirect evidence shows that one of these histones, name, corresponds to H4 in other species. We present evidence that histones is ...
Unambiguous identification of histone H1 in Trypanosoma cruzi
The existence of histone H1 has been questioned in Trypanosomatids. We report here the presence of a histone H1 in the chromatin of Trypanosoma cruzi. This protein was purified by narrow‐bore reversed phase HPLC and its ...
Histone Deacetylase 1 Is Essential for Rod Photoreceptor Differentiation by Regulating Acetylation at Histone H3 Lysine 9 and Histone H4 Lysine 12 in the Mouse Retina
(Amer Soc Biochemistry Molecular Biology Inc, 2017)
Histone acetylation has a regulatory role in gene expression and is necessary for proper tissue development. To investigate the specific roles of histone deacetylases (HDACs) in rod differentiation in neonatal mouse retinas, ...
An updated map of Trypanosoma cruzi histone post-translational modifications
(Nature Research, 2021)
Functional responses and molecular mechanisms involved in histone-mediated platelet activation
(Schattauer Gmbh-Verlag Medizin Naturwissenschaften, 2013-11)
Histones are highly alkaline proteins found in cell nuclei and they can be released by either dying or inflammatory cells. The recent observations that histones are major components of neutrophil extracellular traps and ...