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Síntese de glicoaminoácidos de interesse biológico
(Sociedade Brasileira de Química, 2008)
This work describes the synthesis of the glycosylated amino acids αGlcNAc-Thr, βGlcNAc-Thr and αLacNAc-Thr by the glycosylation reaction of the amino acid threonine with the corresponding glycosyl donors ...
Regulation of self-glycosylation of reversibly glycosylated polypeptides from Solarum tuberosum
(Wiley Blackwell Publishing, Inc, 2004-04-13)
Reversibly glycosylated polypeptides (RGPs) belong to a family of self-glycosylating proteins believed to be involved in plant polysaccharide synthesis. The precise function of these enzymes remains to be elucidated. Our ...
Regioselectivity of glycosylation reactions of galactose acceptors: an experimental and theoretical study
(Beilstein-Institut, 2019-12)
Regioselective glycosylations allow planning simpler strategies for the synthesis of oligosaccharides, and thus reducing the need of using protecting groups. With the idea of gaining further understanding of such ...
Experimental and theoretical study of the O3/O4 regioselectivity of glycosylation reactions of glucopyranosyl acceptors
(Pergamon-Elsevier Science Ltd, 2020-12)
The knowledge of the regioselectivity between different hydroxyl groups of glycosyl acceptors is valuable in planning simple strategies for the synthesis of oligosaccharides, minimizing the use of protecting groups. With ...
Synthetic tools for the characterization of galactofuranosyl transferases. Glycosylations via acylated glycosyl iodides
(Elsevier, 2013-06-07)
With the aim to develop synthetic tools for the characterization of galactofuranosyltransferases, the synthesis of 9-decenyl glycosides of D-Manp, D-Galf and beta-D-Galf-(1,3)-D-Manp was targeted. The interest in the alkenyl ...
Selective glycosylations with furanosides
(Wiley VCH Verlag, 2017)
This chapter focuses on recent advances in the furanose glycosylation field, including its scope and limitations. The findings in the furanose glycosylation field usually follow the findings on pyranose compounds. The ...
Dihydrocucurbitacin B: Semisynthesis of new glicoside derivatives
(Sociedade Brasileira de Química, 2015-01)
In the last ten years, the interest in natural and semi-synthetic cucurbitacin derivatives has increased, primarily due their cytotoxic and anti-tumoral activities. However, the isolation of glycosylated cucurbitacins has ...
Novel and facile solution-phase synthesis of 2,5-diketopiperazines and O-glycosylated analogs
(PERGAMON-ELSEVIER SCIENCE LTD, 2009)
This work describes the synthesis in Solution of a series of related diketopiperazines with potential biological activities: cyclo(L-Pro-L-Ser), cyclo(L-Phe-L-Ser), cyclo(D-Phe-L-Ser) and the corresponding glycosylated ...
Synthesis of Thiodisaccharide Sulfoxides and Sulfones – Determination of the Configuration of the Sulfur Stereocentre
(Wiley VCH Verlag, 2013-11)
The oxidation of per-O-acetyl (1,3)- and (1,4)-linked thiodisaccharides containing glucose, gulose and galactose residues, with an excess of m-chloroperbenzoic acid afforded the corresponding sulfoxides or sulfones. The ...