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GluN2B and GluN2A containing NMDAR are differentially involved in extinction memory destabilization and restabilization during reconsolidation
(Springer Science and Business Media LLC, 2021-01-08)
NMDA Receptor Subunits Change after Synaptic Plasticity Induction and Learning and Memory Acquisition
(Hindawi Publishing Corporation, 2017-07)
NMDA ionotropic glutamate receptors (NMDARs) are crucial in activity-dependent synaptic changes and in learning and memory. NMDARs are composed of two GluN1 essential subunits and two regulatory subunits which define their ...
Hippocampal NMDA receptors and the previous experience effect on memory
(Elsevier, 2014-09)
N-methyl-D-aspartate receptors (NMDAR) are thought to be responsible for switching synaptic activity specific patterns into long-term changes in synaptic function and structure, which would support learning and memory. ...
Effects of a Flavonoid-Rich Fraction on the Acquisition and Extinction of Fear Memory: Pharmacological and Molecular Approaches
(Frontiers Media Sa, 2016-01-05)
The effects of flavonoids have been correlated with their ability to modulate the glutamatergic, serotoninergic, and GABAergic neurotransmission: the major targets of these substances are N-methyl-D-aspartic acid receptor ...
GluN1 and GluN2A NMDA receptor subunits increase in the hippocampus during memory consolidation in the rat
(Frontiers Media S.A., 2017-01)
It is widely accepted that NMDA receptors (NMDAR) are required for learning and memory formation, and for synaptic plasticity induction. We have previously shown that hippocampal GluN1 and GluN2A NMDAR subunits significantly ...
Papel de mTOR, BDNF, AMPAR E NMDAR na reconsolidação da memória de extinção
(BrasilUFRNPROGRAMA DE PÓS-GRADUAÇÃO EM PSICOBIOLOGIA, 2019-03-15)
Memory reactivation can induce two apparently competing processes,
namely extinction and reconsolidation. Extinction involves reduction of a
previously acquired response to a stimulus through formation of a new memory
trace. ...
Exo70 protects against memory and synaptic impairments following mild traumatic brain injury
(2023)
Mild traumatic brain injury (mTBI) is damage to the brain due to external forces. It is the most frequent form of brain trauma and a leading cause of disability in young adults. Hippocampal glutamatergic transmission and ...
Surface expression of NMDA receptor changes during memory consolidation in the crab Neohelice granulata
(Cold Spring Harbor Laboratory Press, 2016-08)
The aim of the present study was to analyze the surface expression of the NMDA-like receptors during the consolidation of contextual learning in the crab Neohelice granulata. Memory storage is based on alterations in the ...
Regulation of Phosphorylated State of NMDA Receptor by STEP61 Phosphatase after Mild-Traumatic Brain Injury: Role of Oxidative Stress
(2021)
Traumatic Brain Injury (TBI) mediates neuronal death through several events involving many molecular pathways, including the glutamate-mediated excitotoxicity for excessive stimulation of N-methyl-D-aspartate receptors ...