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The Wing-Spot and the Comet Tests as Useful Assays Detecting Genotoxicity in Drosophila
(HUMANA PRESS INC, 2013)
Mutagenic and genotoxic effect of hydroxyurea
(International Journal Of Biomedical Science : Ijbs, 2011)
The hydroxyurea, a cytotoxic drug, is the mainly available therapeutical strategy for the treatment of sickle cell disease. This study aimed to evaluate the mutagenic and genotoxic potential of the hydroxyurea through the ...
Chemoprevention assessment, genotoxicity and cytotoxicity of flavonoids from Inga laurina leaves (FABACEAE)
(2019-01-01)
This study aimed to identify and evaluate the cytotoxicity, genotoxicity, antigenotoxicity and chemoprevention assessment of flavonoids myricetin-3-O-(2″-O-galloyl)-α-rhamnopyranoside and myricetin-3-rhamnoside from Inga ...
Using the comet and micronucleus assays for genotoxicity studies: a review
(2015)
Physical, chemical and biological agents can act in the DNA, resulting in mutation involved in cancer. Thus, genotoxic tests are required by regulatory agencies in order to evaluate potential risk of cancer. Among these ...
Analysis of Aloe vera cytotoxicity and genotoxicity associated with endodontic medication and laser photobiomodulation
(2018-01-01)
This study aims to evaluate, in vitro, the effect of Aloe vera associated with endodontic medication, with or without laser photobiomodulation (FTL) irradiation in FP6 human pulp fibroblasts. The materials were divided ...
Mutagenic and genotoxic effect of hydroxyurea
(2011-12-15)
The hydroxyurea, a cytotoxic drug, is the mainly available therapeutical strategy for the treatment of sickle cell disease. This study aimed to evaluate the mutagenic and genotoxic potential of the hydroxyurea through the ...
Mutagenic and genotoxic effect of hydroxyurea
(2011-12-15)
The hydroxyurea, a cytotoxic drug, is the mainly available therapeutical strategy for the treatment of sickle cell disease. This study aimed to evaluate the mutagenic and genotoxic potential of the hydroxyurea through the ...
An evaluation of the genotoxic and cytotoxic effects of the anti-obesity drugs sibutramine and fenproporex
(SAGE PUBLICATIONS LTD, 2010)
Anti-obesity medications deserve special considerations at the present time due to an increasing number of overweight and obese people who require these therapeutic alternatives. Obesity is positively associated with several ...
Genotoxic potential of the latex from cotton-leaf physicnut (Jatropha gossypiifolia L.)
(Soc Brasil Genetica, 2015-01-01)
Jatropha gossypiifolia L. (Euphorbiaceae), popularly known as cotton-leaf physicnut, is a milky shrub notable for its medicinal properties. The present study aimed to evaluate the toxic, cytotoxic and genotoxic effects of ...